312615-23-9Relevant academic research and scientific papers
Synthesis of 5- and 6-substituted 2-(4-dimethylaminophenyl)-1,3-benzoxazoles and their in vitro and in vivo evaluation as imaging agents for amyloid plaque
Hausner, Sven H.,Alagille, David,Koren, Andrei O.,Amici, Louis,Staley, Julie K.,Cosgrove, Kelly P.,Baldwin, Ronald M.,Tamagnan, Gilles D.
scheme or table, p. 543 - 545 (2011/03/20)
A series of novel 5- and 6-substituted 2-(4-dimethylaminophenyl)-1,3-benzoxazoles was synthesized and their potential as imaging probes for Alzheimer's Disease (AD)-related amyloid plaque was evaluated in vitro and in vivo. In vitro binding affinities for
