312695-87-7

Upstream product

• 289472-92-0 (2S)-2-(2,2-dibromo-vinyl)-4-methyl-3,6-dihydro-2H-pyran 
• 312695-95-7 [bis-(2,2,2-trifluoro-ethoxy)-phosphoryl]-acetic acid 1-[1-(4-methoxy-benzyloxy)-3-(4-methyl-3,6-dihydro-2H-pyran-2-yl)-allyl]-5-methoxymethoxy-7-{2-methyl-3-[6-(2-oxo-ethyl)-3,6-dihydro-2H-pyran-2-yl]-propyl}-octa-3,7-dienyl ester 
• 349539-76-0 (E)-(1R,7S,11S,15S,17R)-7-[(E)-(S)-1-(4-Methoxy-benzyloxy)-3-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-allyl]-11-methoxymethoxy-15-methyl-13-methylene-6,21-dioxa-bicyclo[15.3.1]henicosa-9,19-dien-3-yn-5-one 
• 312695-86-6 (3E,9E)-(1R,7S,11S,15S,17R)-7-[(E)-(S)-1-(4-Methoxy-benzyloxy)-3-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-allyl]-11-methoxymethoxy-15-methyl-13-methylene-6,21-dioxa-bicyclo[15.3.1]henicosa-3,9,19-trien-5-one 
• 349539-71-5 4-{6-[11-(4-methoxy-benzyloxy)-6-methoxymethoxy-2-methyl-13-(4-methyl-3,6-dihydro-2H-pyran-2-yl)-4-methylene-10-(tetrahydro-pyran-2-yloxy)-trideca-7,12-dienyl]-5,6-dihydro-2H-pyran-2-yl}-but-2-ynoic acid methyl ester 
• 394657-63-7 C₄₄H₆₂Br₂O₈ 
• 349539-69-1 2-{(2R,6R)-6-[(7E,12E)-(2S,6S,10S,11S)-11-(4-Methoxy-benzyloxy)-6-methoxymethoxy-2-methyl-13-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-4-methylene-10-(tetrahydro-pyran-2-yloxy)-trideca-7,12-dienyl]-5,6-dihydro-2H-pyran-2-yl}-ethanol 
• 394657-62-6 {(2R,6R)-6-[(7E,12E)-(2S,6S,10S,11S)-11-(4-Methoxy-benzyloxy)-6-methoxymethoxy-2-methyl-13-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-4-methylene-10-(tetrahydro-pyran-2-yloxy)-trideca-7,12-dienyl]-5,6-dihydro-2H-pyran-2-yl}-acetaldehyde 
• 349539-73-7 4-{(2R,6R)-6-[(7E,12E)-(2S,6S,10S,11S)-10-Hydroxy-11-(4-methoxy-benzyloxy)-6-methoxymethoxy-2-methyl-13-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-4-methylene-trideca-7,12-dienyl]-5,6-dihydro-2H-pyran-2-yl}-but-2-ynoic acid 
• 385809-16-5 (2R,6R)-tert-butyl-[2-(6-{4-[(2S)-3-(4-methoxybenzyloxy)-2-methoxymethoxy-propyl]-[(2S)-2-methylpent-4-enyl]}-5,6-dihydro-2H-pyran-2-yl)-ethoxy]-dimethylsilane 
• 312695-91-3 (2S)-4-(3-{(2R,6R)-6-[2-(tert-butyldimethylsilanyloxy)-ethyl]-3,6-dihydro-2H-pyran-2-yl}-(2S)-2-methylpropyl)-2-methoxymethoxy-pent-4-en-1-ol 
• 312695-75-3 [(2R,6R),(2S),2S]-4-(3-{6-[2-(tert-butyldimethylsilanyloxy)-ethyl]-3,6-dihydro-2H-pyran-2-yl}-2-methylpropyl)-2-methoxymethoxypent-4-enal 
• 312695-82-2 (2S)-2-{(E)-2-[(4S,5S)-5-(2-benzenesulfonyl-ethyl)-2-(4-methoxy-phenyl)-[1,3]dioxolan-4-yl]-vinyl}-4-methyl-3,6-dihydro-2H-pyran 
• 312695-77-5 (2R,6S)-(2-{6-[(2R)-3-benzyloxy-2-methyl-propyl]-5,6-dihydro-2H-pyran-2-yl}-ethoxy)-tert-butyl-dimethyl-silane 

Downstream Products

• 312695-96-8 (1R,3Z,7S,9E,11S,15S,17R)-11-hydroxy-7-{(1S,2E)-1-(4-methoxybenzyloxy)-3-[(2S)-4-methyl-3,6-dihydro-2H-pyran-2-yl]allyl}-15-methyl-13-methylene-6,21-dioxabicyclo[15.3.1]henicosa-3,9,19-trien-5-one 
• 312695-97-9 (Z)-(1R,3S,7S,8S,10S,12S,18R)-7-Hydroxy-12-[(E)-(S)-1-(4-methoxy-benzyloxy)-3-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-allyl]-3-methyl-5-methylene-9,13,22-trioxa-tricyclo[16.3.1.0^8,10]docosa-15,19-dien-14-one 
• 115268-43-4 laulimalide 

Relevant academic research and scientific papers

A macrolactonization-based strategy to obtain microtuble-stabilizing agent (-)-laulimalide

An alternative synthesis of anti-tumor macrolide (-)-laulimalide is described. The synthesis was achieved utilizing Yamaguchi macrolactonization as the key step. The sensitive C2-C3 cis-olefin functionality has been installed by a ma