31274-15-4Relevant academic research and scientific papers
Manganese-Catalyzed Electrochemical Deconstructive Chlorination of Cycloalkanols via Alkoxy Radicals
Allen, Benjamin D. W.,Hareram, Mishra Deepak,Seastram, Alex C.,McBride, Tom,Wirth, Thomas,Browne, Duncan L.,Morrill, Louis C.
supporting information, p. 9241 - 9246 (2019/11/19)
A manganese-catalyzed electrochemical deconstructive chlorination of cycloalkanols has been developed. This electrochemical method provides access to alkoxy radicals from alcohols and exhibits a broad substrate scope, with various cyclopropanols and cyclobutanols converted into synthetically useful β- and γ-chlorinated ketones (40 examples). Furthermore, the combination of recirculating flow electrochemistry and continuous inline purification was employed to access products on a gram scale.
Tandem decarboxylative allylation and fragmentation of allyl benzocyclobutenyl carbonates: Access to ortho-functionalized aryls from aryl bromides
Rosa, David,Chtchemelinine, Andrei,Orellana, Arturo
experimental part, p. 1885 - 1891 (2012/08/14)
Allyl benzocyclobutyl carbonates yield ortho-allyl α-aryl ketones through a palladium-catalyzed decarboxylative allylation, fragmentation, and cross-coupling process. Georg Thieme Verlag Stuttgart · New York.
Preparation of benzocyclobutenols by low temperature reaction of ketone enolates with benzynes
Tripathy, Sasmita,Reddy, Ranga,Durst, Tony
, p. 997 - 1002 (2007/10/03)
The reaction of benzynes, generated from halobenzenes with lithium tetramethylpipiperide (LTMP) at -40 to -78°C, with ketone enolates affords benzocyclobutenols in fair to good yields.
Template Aggregative Activation: Metal Salt-reinforced Complex Bases in Arynic Synthesis
Fort, Yves,Christophe, Stephanie,Caubere, Paul
, p. 334 - 335 (2007/10/03)
A substantial effect on the reactivity of a common complex base is observed by the addition of metal salts MXn (M = Mg, Zn, Cu, Zr); a template effect of the new aggregates is proposed.
DECOMPOSITION ACIDO-CATALYSEE D'AZIDES TERTIAIRES BENZOCYCLOBUTENIQUES. NOUVELLE METHODE DE SYNTHESE DU NOYAU INDOLIQUE PAR EXTENSION DU CYCLE
Adam, G.,Andrieux, J.,Plat, M
, p. 399 - 408 (2007/10/02)
Treatment of benzocyclobutenols substituted on the functional carbon by the HN3/BF3-Et2O reagent allows the synthesis to the corresponding tertiary azides.The latter by acid-catalysed breakdown, lead to 2-substituted indoles.A similar result is obtained by treating directly the alcohols with hydrazoic acid and concentrated sulfuric acid.This new route to indole nucleus is also extended to the synthesis of policyclic indoles.
