312754-10-2Relevant academic research and scientific papers
An investigation into the structure-activity relationships associated with the systematic modification of the β2-adrenoceptor agonist indacaterol
Beattie, David,Beer, David,Bradley, Michelle E.,Bruce, Ian,Charlton, Steven J.,Cuenoud, Bernard M.,Fairhurst, Robin A.,Farr, David,Fozard, John R.,Janus, Diana,Rosethorne, Elizabeth M.,Sandham, David A.,Sykes, David A.,Trifilieff, Alexandre,Turner, Katharine L.,Wissler, Elke
, p. 6280 - 6285 (2012/10/30)
The synthesis of a series of indacaterol analogues in which each of the three structural regions of indacaterol are modified in a systematic manner is described. Evaluation of the affinity of these analogues for the β2-adrenoceptor identified t
Beta2-adrenoceptor agonists
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Page/Page column 24, (2008/06/13)
Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways diseases.
