312757-07-6Relevant academic research and scientific papers
Bisketene Equivalents as Diels-Alder Dienes
Dissanayake, Isuru,Hart, Jacob D.,Becroft, Emma C.,Sumby, Christopher J.,Newton, Christopher G.
, p. 13328 - 13333 (2020)
2,5-Bis(tert-butyldimethylsilyloxy)furans are established as vicinal bisketene equivalents for application as dienes in the Diels-Alder reaction. Cycloaddition with olefinic dienophiles, under exceptionally mild conditions, enables convergent access to highly substituted para-hydroquinones in unprotected form via a one-pot Diels-Alder/ring-opening/tautomerization sequence. The synthesis of para-benzoquinones from acetylenic dienophiles, including benzynes, is also demonstrated, and 2,5-bis(tert-butyldimethylsilyloxy)pyrroles are established as competent dienes for the synthesis of para-iminoquinones. Application in natural product synthesis enables gram-scale access to the neuroprotective agent (±)-indanostatin.
Substituted isoindoles
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, (2008/06/13)
This invention relates to novel compounds of the formulae and their use as herbicides: STR1 wherein X is H, F, Cl, Br, CN, NO2 or OCH3 ; Y is H, F, or CH3 ; and Z is H, F, Cl, Br or OCH3 provided that (1) when Y
