31295-49-5Relevant academic research and scientific papers
NUCLEOPHILIC CLEAVAGE AND FORMATION OF SATURATED HETEROCYCLES. IX. KINETICS OF THE AMINATION OF 1-AZIRIDINE
Bobylev, V. A.,Dalin, A. R.,Borisenko, I. V.,Kamskaya, O. I.
, p. 1003 - 1007 (2007/10/02)
1.Enlarging the aminoethyl substituent at the heteroatom of the aziridine ring results in a decrease in reactivity and an increase in substrate selectivity towards nucleophilic cleavage by amines. 2.The reactivity of amines in the nucleophilic cleavage of 1-aziridine is largely governed by the steric accessibility of the nitrogen atoms of the nucleophile.Amino groups in which the environment of the reaction site is the same have similar reactivities.
