313270-75-6Relevant academic research and scientific papers
N-(3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop[f] isoindol-2-(1H)-yl)carboxamides: Identification of novel orthopoxvirus egress inhibitors
Bailey, Thomas R.,Rippin, Susan R.,Opsitnick, Elizabeth,Burns, Christopher J.,Pevear, Daniel C.,Collett, Marc S.,Rhodes, Gerry,Tohan, Sanjeev,Huggins, John W.,Baker, Robert O.,Kern, Earl R.,Keith, Kathy A.,Dai, Dongcheng,Yang, Guang,Hruby, Dennis,Jordan, Robert
, p. 1442 - 1444 (2007)
A series of novel, potent orthopoxvirus egress inhibitors was identified during high-throughput screening of the ViroPharma small molecule collection. Using structure-activity relationship information inferred from early hits, several compounds were synth
PHARMACEUTICAL COMPOSITION FOR USE IN THE TREATMENT AND PREVENTION OF ORTHOPOXVIRUS INFECTIONS AND ASSOCIATED DISEASES
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Paragraph 0086; 0087, (2016/08/03)
Pharmaceutical compositions containing di, tri, and tetracyclic acylhydrazide derivatives of the formula below, for use in the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the orthopoxvirus.
