313274-77-0Relevant academic research and scientific papers
Synthesis and in vivo diuretic activity of biphenyl benzothiazole-2- carboxamide derivatives
Yar, Mohammad Shahar,Ansari, Zaheen Hasan
experimental part, p. 387 - 392 (2010/01/14)
A series of N-{(substituted)1,3-benzothiazol-2-yl}-1,1'-biphenyl-4- carboxamides was synthesized by reaction between biphenyl acid chloride and 2-aminobenzothiazole. The synthesized compounds were screened in vivo for diuretic activity. Among the series, N-(1,3-benzothiazol-2-yl)-1,1'-biphenyl-4- carboxamide (II) was found to be the most promising candidate.
