313276-45-8Relevant academic research and scientific papers
Oxidation of thiazolo[3,2-a]pyrimidin-3(2H)-ones with DMSO and Lawesson's reagent
Lashmanova, Eugenia A.,Kirdyashkina, Anastasiya I.,Slepukhin, Pavel A.,Shiryaev, Andrey K.
supporting information, p. 1099 - 1103 (2018/02/19)
2,2′-Dimers with a central double bond were prepared by the oxidation of 5,6-disubstituted 7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-3(2H)-ones with DMSO and Lawesson's reagent at room temperature. The role of DMSO as an oxidizing reagent was confirmed by NMR spectroscopy. The E-configuration of the central C[dbnd]C bond for the two diastereomers of compound 8m was proven by single crystal X-ray data. The dimeric thiazolopyrimidines were orange or red colored and absorption bands at 283–330 and 459–476 nm were observed in the UV spectra.
Synthesis of ethyl-5-(substituted phenyl)-7-methyl-3-oxo-3,5-dihydro-2H- thiazolo[3,2-a]-pyrimidine-6-carboxylates
Pathak, Arun,Narayanaswamy, Venugopala Katharigatta,Joshi, Aakanksha,Rao, Gopal Krishna,Devi, Kalpana
experimental part, p. 273 - 276 (2011/12/14)
A series of ethyl-5-(substituted phenyl)-7-methyl-3-oxo-3,5-dihydro-2H- thiazolo [3,2-a] pyrimidine-6-carboxylates (2a-l) were synthesized by cyclocondensation of ethyl-6-methyl-4-(substituted phenyl)-2-thioxo-1,2,3,4- tetrahydropyrimidine-5-carboxylates,
