313342-45-9

Upstream product

• 65926-39-8 (R)-benzyl 2-(((benzyloxy)carbonyl)amino)-3-iodopropanoate 
• 313342-43-7 (1,1-diethoxy-ethyl)-(4-iodo-benzyl)-phosphinic acid ethyl ester 
• 21209-51-8 N-benzyloxycarbonyl-L-serine benzyl ester 
• 16004-15-2 1-bromomethyl-4-iodobenzene 
• 122085-76-1 ethyl (1,1-diethoxyethyl)phosphinate 

Downstream Products

• 313342-62-0 3-{4-[ethoxy-(hydroxy-phenyl-methyl)-phosphinoylmethyl]-phenyl}-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid benzyl ester 
• 313342-58-4 (S)-2-Benzyloxycarbonylamino-3-{4-[ethoxy-(phenyl-trimethylsilanyloxy-methyl)-phosphinoylmethyl]-phenyl}-propionic acid benzyl ester 
• 313342-41-5 2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-{4-[hydroxy-(hydroxy-phenyl-methyl)-phosphinoylmethyl]-phenyl}-propionic acid 
• 313342-61-9 3-[4-(benzyl-ethoxy-phosphinoylmethyl)-phenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid 
• 313342-42-6 3-[4-(benzyl-hydroxy-phosphinoylmethyl)-phenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid 
• 313342-57-3 (S)-3-[4-(Benzyl-ethoxy-phosphinoylmethyl)-phenyl]-2-benzyloxycarbonylamino-propionic acid benzyl ester 
• 313342-56-2 (S)-2-Benzyloxycarbonylamino-3-[4-(ethoxy-methyl-phosphinoylmethyl)-phenyl]-propionic acid benzyl ester 
• 313342-60-8 (S)-2-Benzyloxycarbonylamino-3-[4-(hydroxy-methyl-phosphinoylmethyl)-phenyl]-propionic acid 
• 313342-47-1 (S)-2-Benzyloxycarbonylamino-3-(4-ethoxyphosphinoylmethyl-phenyl)-propionic acid benzyl ester 

Relevant academic research and scientific papers

Structure-based design and synthesis of phosphinate isosteres of phosphotyrosine for incorporation in Grb2-SH2 domain inhibitors. Part 2

A series of novel phosphinates, derived from 4-phosphonomethylphenylalanine, are described as isosteres of phosphotyrosine. Benzyl (or alkyl) phosphinomethylphenylalanine derivatives were prepared by alkylation of an amino acid P-H phosphinate. (C) 2000 Elsevier Science Ltd.