313386-92-4Relevant academic research and scientific papers
Novel T-type calcium channel blockers: Dioxoquinazoline carboxamide derivatives
Jo, Mi Na,Seo, Hee Jeong,Kim, Yoonji,Seo, Seon Hee,Rhim, Hyewhon,Cho, Yong Seo,Cha, Joo Hwan,Koh, Hun Yeong,Choo, Hyunah,Pae, Ae Nim
, p. 365 - 373 (2007)
T-type calcium channel is one of therapeutic targets for the treatment of cardiovascular diseases and neuropathic pains. Since the withdrawal of mibefradil, a T-type calcium channel blocker, there have been a lot of efforts to develop T-type calcium chann
PHARMACEUTICAL COMPOSITIONS CONTAINING QUINAZOLINE DERIVATIVES FOR TREATING AS SEROTONIN RECEPTOR ANTAGONIST
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, (2009/07/02)
The present invention relates to a pharmaceutical composition containing one or more quinazoline compounds as an active ingredient, which has antagonistic activity against serotonin 5-HT3A and is effective for the prevention and treatment of ce
2,4-QUINAZOLINE DERIVATIVES HAVING ACTIVITY TO T-TYPE CALCIUM CHANNEL AND PREPARATION METHOD THEREOF
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Page/Page column 24-25, (2008/06/13)
Disclosed are 2,4-dioxo-quinazoline derivative compounds of Formula 1 which is a selective antagonist with respect to a T-type calcium channel and can be developed as a drug for neurogenic pains, epilepsy or hypertension, and a preparation method thereof.
