313518-12-6 Usage
General Description
The chemical compound "(2-[(2-Phenoxyethyl)thio]-1H-benzimidazol-1-yl)acetic acid" is an organic compound. It is a benzimidazole derivative that contains a benzimidazole core with a thioether link and an acetic acid side chain. The compound has potential pharmaceutical applications due to its benzimidazole moiety, which is known for its biological activities such as antimicrobial, antifungal, antiviral, and anticancer properties. The presence of the acetic acid side chain also provides the compound with potential binding and functional properties in biological systems. Therefore, this compound may be of interest for further study and development in the pharmaceutical and medicinal chemistry fields.
Check Digit Verification of cas no
The CAS Registry Mumber 313518-12-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,3,5,1 and 8 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 313518-12:
(8*3)+(7*1)+(6*3)+(5*5)+(4*1)+(3*8)+(2*1)+(1*2)=106
106 % 10 = 6
So 313518-12-6 is a valid CAS Registry Number.
313518-12-6Relevant articles and documents
Novel 2-(2-(benzylthio)-1H-benzo[d]imidazol-1-yl)acetic acids: Discovery and hit-to-lead evolution of a selective CRTh2 receptor antagonist chemotype
Pothier, Julien,Riederer, Markus A.,Peter, Oliver,Leroy, Xavier,Valdenaire, Anja,Gnerre, Carmela,Fretz, Heinz
supporting information; experimental part, p. 4660 - 4664 (2012/08/07)
Hit-to-lead evolution of 2-(2-((2-(4-chlorophenoxy)ethyl)thio)-1H-benzo[d] imidazol-1-yl)acetic acid (1), discovered in a high-throughput screening campaign as a novel chemotype of CRTh2 receptor antagonist, is presented. SAR development as well as in vitro and in vivo DMPK properties of selected representatives of substituted 2-(2-(benzylthio)-1H-benzo[d]imidazol-1-yl)acetic acids are discussed.
