31352-82-6Relevant academic research and scientific papers
Pyrazolodiazepines. 2. 4-Aryl-1,3-dialkyl-6,8-dihydropyrazolo[3,4-e][1,4]diazepin-7(1H)-ones as antianxiety and anticonvulsant agents
DeWald,Lobbestael,Butler
, p. 1562 - 1569 (2007/10/05)
A series of 4-aryl-1,3-dialkyl-6,8-dihydropyrazolo[3,4-e][1,4] diazepin-7(1H)-ones was synthesized and screened for psychotropic activity. In animals, a number of these pyrazolodiazepinones had strong CNS effects similar to diazepam. One compound, 4-(2-fluorophenyl)-6,8-dihydro-1,3,8 trimethylpyrazolo[3,4-e][1,4)diazepin-7(1H)-one (54), is being studied in the clinic as a component of a new animal anesthetic Tilazol.
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