313644-40-5

Upstream product

• 909797-73-5 C₂₂H₂₈N₂O₈ 
• 145325-44-6 1',4'-bis<2-methoxy-(4-methoxycarbonyl)-5-nitrophenoxy>butane 
• 1016557-31-5 C₂₂H₂₄N₆O₈ 

Downstream Products

• 313644-46-1 C₃₀H₃₄N₈O₈ 
• 1016557-34-8 C₃₀H₃₄N₈O₁₀ 
• 313644-42-7 C₃₂H₃₈N₈O₁₀ 

Relevant academic research and scientific papers

A facile intramolecular azido/amido reductive cyclization approach: synthesis of pyrrolobenzodiazepines and their dimers

A new synthetic pathway has been developed for the preparation of imine-containing pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) and their dimers. Selective reduction of aromatic azides as well as aliphatic amides in a single step leading to an intramolecular

Synthesis of pyrrolo[2,1-c][1,4]benzodiazepines via reductive cyclization of ω-Azido carbonyl compounds by TMSI: An efficient preparation of antibiotic DC-81 and its dimers

ω-Azido carbonyl compounds on reaction with trimethylsilyl iodide (in situ prepared from TMSCI/NaI) led to the formation of diazepine imines in good yields under mild conditions. This methodology has been applied to the parent unsubstituted pyrrolobenzodiazepine, the natural product DC-81 and its dimers. (C) 2000 Elsevier Science Ltd.