31385-80-5Relevant academic research and scientific papers
Synthesis and anti-inflammatory, analgesic, ulcerogenic and cyclooxygenase activities of novel quinazolinyl-Δ2-pyrazolines
Kumar, Ashok,Sharma, Shalabh,Bajaj, Kiran,Bansal, Deepti,Sharma, Shipra,Saxena, Archana K. K.,Lata,Gupta,Srivastava
, p. 1979 - 1984 (2007/10/03)
Synthesis of 2-(ω -chloroacetonyl)-3-substituted-phenyl-6-halo/6,8-dihaloquinazolin-4(3H)-ones 6-10, 2-(ω -hydrazinoacetonyl)-3-substituted-phenyl-6-halo/6,8-dihaloquinazolin-4(3H)ones 11-15 and 1′ -[3H-3-substituted-phenyl-4-oxo-6-halo/6,8-dihaloquinazolin-2-acetonyl] -3′-aryl-5′-(2-substituted-indol-3-yl)-Δ 2-pyrazolines 16-30 have been described. All the compounds have been tested in vivo for their anti-inflammatory, analgesic, ulcerogenic activities and acute toxicity.
Reactions with 3,1-Benzoxazin-4-ones. 3. Reactions of 6,8-Dibromo-2-methyl-3,1-benzoxazin-4-ones with Amines
Ismail, M. Fekry,Shams, Nabil A.,Salem, M. R.,Emara, S. A.
, p. 4172 - 4174 (2007/10/02)
We observed that the reactions of 6,8-dibromo-2-methyl-3,1-benzoxazin-4-one, 5, with primary amines occurs very slowly in ethanol solution at room temperature and that the product is usually the corresponding 2-acetamido-3,5-dibromobenzamide, 6.These resu
