31390-64-4 Usage
Uses
Used in Pharmaceutical Industry:
(4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-sulfide is used as a potential pharmaceutical candidate for [application reason] due to its complex structure and the presence of a purine base, which is a key component of DNA and RNA.
Used in Chemical Research:
(4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-sulfide is used as a subject of chemical research for [application reason] to explore its unique chemical properties and potential applications.
Note: The specific application reasons for the pharmaceutical industry and chemical research are not provided in the materials. Further research is needed to determine the exact uses and benefits of (4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-sulfide in these fields.
Check Digit Verification of cas no
The CAS Registry Mumber 31390-64-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,3,9 and 0 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 31390-64:
(7*3)+(6*1)+(5*3)+(4*9)+(3*0)+(2*6)+(1*4)=94
94 % 10 = 4
So 31390-64-4 is a valid CAS Registry Number.
31390-64-4Relevant academic research and scientific papers
Stereoselective preparation of (RP)-8-hetaryladenosine-3′, 5′-cyclic phosphorothioic acids
Andrei, Mioara,Bjornstad, Vidar,Langli, Geir,Romming, Christian,Klaveness, Jo,Tasken, Kjetil,Undheim, Kjell
, p. 2070 - 2080 (2008/03/12)
Cyclic adenosine monophosphate (cAMP) has been converted into its 8-bromo derivative and 2′O-TBDMS protected before activation of the phosphoric acid moiety with a reagent generated in situ from oxalyl chloride and DMF. Further reactions with primary amines furnished corresponding phosphoramidates with high stereoselectivity at the phosphorus atom. Cross-coupling reactions with the 8-bromopurine yielded 8-hetaryl derivatives. X-Ray analyses showed the amidates to possess the (SP)-configuration. Carbon disulfide effected thiylation under strongly basic conditions stereospecifically provided the (RP)-phosphorothioic acids. The Royal Society of Chemistry.
Synthesis of ribonucleoside 3',5'-cyclic phosphorothioates using a modified hydroxybenzotriazole phosphotriester approach
Vroom, E. de,Marel, G. A. van der,Boom, J. H. van
, p. 577 - 580 (2007/10/02)
Phosphorothioylation of 3',5'-dihydroxy ribonucleosides with O-(2-chlorophenyl) O,O-bis phosphorothioate, followed by addition of N-methylimidazole and removal of protecting groups, gives ribonucleosides 3',5'-cyclic
