31396-94-8

Usage

Molecular structure

Pyrrole derivative
Two benzyl groups attached to the nitrogen atom
One methyl group attached to the nitrogen atom
Two phenyl groups attached to the 3 and 4 positions of the pyrrole ring

Potential applications

Organic synthesis
Medicinal chemistry
Material science

Possible properties

Exhibits biological activity
Could be used as a building block for the synthesis of complex organic molecules
Unique structural features that may be useful in the development of advanced materials with specific electronic or optical properties

Upstream product

• 113123-14-1 N-(1-Benzyl-2-phenyl-ethylidene)-N'-methyl-hydrazine 
• 102-04-5 1,3-Diphenylpropanone 

Relevant academic research and scientific papers

Reaction of Ketone Alkylhydrazones with Phosphorus Trichloride: a General Mild Route to Substituted Pyrroles

A new convinient and mild procedure for the synthesis of symmetrically and unsymmetrically substituted pyrroles is described.This one-pot synthesis consists of two different stages.The first stage, addition of PCl3 to an alkylhydrazone, is always carried out at room temperature.The second stage, addition of an enolizable ketone to the previous reaction mixture, is performed at room temperature, or at 80 deg C under reduced pressure.The results provide clear evidence that diazaphsphole derivatives being formed in the first stage are intermediates in this pyrrole synthesis.

Synthesis of Pyrroles under Mild Conditions using PCl3, Ketones, and Alkylhydrazines

A one-pot synthesis of symmetrical pyrroles was obtained by reaction of alkylhydrazones of enolizable ketones, PCl3, and subsequent addition of the same ketone.