313967-18-9

Usage

Uses

Used in Pharmaceutical Industry:
FLI-06 is used as a novel inhibitor for [application reason] the inhibition of Notch signaling and the early secretory pathway. This makes it a potential candidate for the development of new therapeutic strategies targeting various diseases and conditions related to the dysregulation of these pathways.
Used in Research and Development:
FLI-06 is used as a research tool for [application reason] studying the mechanisms and functions of Notch signaling and the early secretory pathway. Its unique ability to disrupt the Golgi apparatus and inhibit general secretion at an early stage provides researchers with valuable insights into the cellular processes involved in these pathways.
Used in Drug Discovery:
FLI-06 is used as a lead compound for [application reason] the development of new drugs targeting the Notch signaling pathway and the early secretory pathway. Its distinct mode of action compared to other known inhibitors makes it a promising starting point for the design and synthesis of novel therapeutic agents.
Used in Cell Biology:
FLI-06 is used as a cellular probe for [application reason] investigating the structure and function of the Golgi apparatus and the endoplasmic reticulum. Its ability to induce a morphological transition in the ER provides researchers with a valuable tool for understanding the dynamics and regulation of these important cellular structures.

References

1) Kramer?et al., (2013),?Small molecules intercept Notch signaling and the early secretory pathway; Nat. Chem. Biol.?9 731