31397-09-8

Upstream product

• 98-01-1 furfural 
• 5351-69-9 4-Phenyl-3-thiosemicarbazide 
• 62-53-3 aniline 
• 26152-23-8 furfurylidene-hydrazinecarbodithioic acid methyl ester 
• 103-72-0 phenyl isothiocyanate 

Downstream Products

• 60870-44-2 (5-furan-2-yl-[1,3,4]thiadiazol-2-yl)-phenyl-amine 
• 139355-60-5 5-{[1-Furan-2-yl-meth-(E)-ylidene]-hydrazono}-4-phenyl-[1,2,4]dithiazolidin-3-one 
• 1093399-55-3 4-amino-1-(furan-2-carbonyl)-2,7-dinitro-4'-phenylspiro(fluoren-9,3'-[1,2,4]triazolidine)-5'-thione 
• 84409-01-8 4-amino-2,7-dinitro-9-fluorenone 
• 60870-44-2 5-(furan-2-yl)-N-phenyl-1,3,4-thiadiazole-2-amine 
• 1093399-43-9 3-(furan-2-yl)-4a-hydroxyindeno[2,1-e][1,3,4]oxadiazin-9(4aH)-one 
• 1093399-45-1 3-cyano-4-oxo-N-phenylideno[1,2-c]pyrazole-1(4H)-carbothioamide 
• 109837-80-1 bis(2-furaldehyde-4-phenylthiosemicarbazonato)nickel(II) 
• 101215-29-6 Cd((OC₄H₃)CHNNCSNH(C₆H₅))2 
• 109782-54-9 bis[4-phenyl-1-(furan-2-carbaldehyde) thiosemicarbazonato]palladium(II) 
• 133347-21-4 Ni((OC₄H₃)CHNNCSNH(C₆H₅))2 
• 109782-55-0 bis(2-furaldehyde-4-phenylthiosemicarbazonato)platinum(II) 
• 1174624-62-4 methyl [3-(2-furyl)-4-oxo-1-(phenylthiocarbamoyl)-4,5-dihydro-1H-pyrazol-5-ylidene]ethanoate 
• 1174624-74-8 ethyl 3-amino-6-(2-furyl)-5-cyanopyridazine-4-carboxylate 

Relevant academic research and scientific papers

Synthesis, thermal and antitumour studies of Th(IV) complexes with furan-2-carboxaldehyde4-phenyl-3-thiosemicarbazone

Thorium(IV) complexes with the Schiff base furan-2-carboxaldehyde4phenyl-3- thiosemicarbazone (L) were synthesised and characterized. The composition and structure of the metal complexes were proposed based on elemental analysis, molar conductivity measur

Inhibitory effect of synthetic aromatic heterocycle thiosemicarbazone derivatives on mushroom tyrosinase: Insights from fluorescence, 1H NMR titration and molecular docking studies

Three structurally similar aromatic heterocyclic compounds 2-thiophenecarboxaldehyde (a), 2-furaldehyde (b), 2-pyrrolecarboxaldehyde (c) were chosen and a series of their thiosemicarbazone derivatives(1a-3a, 1b-3b and 1c-3c) were synthesized to evaluate t

Efficient synthesis of novel 2,3-dihydro-1,3,5,4-thiadiazaphosphole derivatives

ABSTRACT: The condensation of various thiosemicarbazones with methyl thiophene-2-carboximidate afforded the corresponding intermediates 2a–2h. Subsequent cyclization of the latter compounds with hexamethylphosphorous triamide constitutes a new route to the synthesis of novel highly functionalized thiadiazaphosphole derivatives 4a–4h. This method offers significant advantages such as efficiency, high yields and mild reaction conditions.

Synthesis and fungicidal activities of some 2-substituted arylamino-5-(2′-furyl)-1,3,4-thiadiazolo[3,2-c]thiazoles and 5-substituted aryl-2-substituted arylamino-1,3,4-thiadiazolo[3,2-c]thiazoles

Several 2-substituted arylamino-5-(2′-furyl)-1,3,4-thiadiazolo[3,2-c] thiazoles have been synthesised by cyclisation of 3-substituted aryl thiocarbanilido-2-(2′-furyl)thiazolidin-4-ones with cone. H 2SO4 with constant stirring in cold and 5-substituted aryl-2-substituted arylamino-1,3,4-thiadiazolo[3,2-c]thiazoles have been synthesised by the cyclisation of 2-substituted aryl-3-substituted arylthiourido-thiazolidin-4-ones with cone. H2SO4 with constant stirring in cold and screened for their antifungal activities against Helminthosporium oryzae and Cephalosporium sacchari.

Synthesis and characterization of new palladium(II) complexes with ligands derived from furan-2-carbaldehyde and benzaldehyde thiosemicarbazone and their in vitro cytotoxic activities against various human tumor cell lines

With the ligands 4-phenyl-1-(furan-2-carbaldehyde)thiosemicarbazone, HTSC', (1), 4-phenyl-1- (5'-phenyl-furan-2-carbaldehyde)thiosemicarbazone, HTSC 2 (2), o-methoxy-benzaldehydethiosemicarbazone, HTSC3 (3), and o-cyano-benzaldehydet

Synthesis and Ribonucleotide reductase inhibitory activity of thiosemicarbazones

Ribonucleotide reductase (RR) is an important therapeutic target for anticancer drugs. The structure of human RR features a 1:1 complex of two homodimeric subunits, hRRM1 and hRRM2. Prokaryotically expressed and highly purified recombinant human RR subunits, hRRM1 and hRRM2, were used for holoenzyme-based [3H]CDP reduction in vitro assay. Ten new thiosemicarbazones (7-16) were synthesized and screened for their RR inhibitory activity. Two thiosemicarbazones derived from p-hydroxy benzaldehyde (9 and 10) were found to be active but less potent than the standard, Hydroxyurea (HU). Guided by the activity of compounds 9 and 10, 11 new thiosemicarbazones (17-27) derived from p-hydroxy benzaldehyde were prepared and screened for their RR inhibitory activity. All the 11 compounds were more potent than HU.

Synthesis and Spectral Studies on Metal Chelates of Heterocyclic Carboxaldehyde Thiosemicarbazones

Spuare-planar neutral metal chelates of aldehyde thiosemicarbazones of the type ML2, where M=NiII, PdII or PtII and HL=thiosemicarbazone or 4-phenyl- or 4-methylthiosemicarbazone of 2-furaldehyde or thiophene-2-carboxaldeh