31408-17-0

Basic information

• Product Name: 5-P-TOLYLPYRIMIDIN-2-YLAMINE
• Synonyms: 5-P-TOLYLPYRIMIDIN-2-YLAMINE;5-p-Tolylpyrimidin-2-ylamine95%;5-P-TOLYLPYRIMIDIN-2-YLAMINE 95%;5-P-tolylpyrimidin-2-amine;5-(4-Methylphenyl)pyriMidin-2-aMine
• CAS NO: 31408-17-0
• Molecular Formula: C₁₁H₁₁N₃
• Molecular Weight: 185.23
• EINECS: 604-604-1
• Mol File: 31408-17-0.mol

Chemical Properties

• Boiling Point: 408.4 °C at 760 mmHg
• Flash Point: 229.8 °C
• Appearance: /
• Density: 1.159 g/cm³
• Vapor Pressure: 7.04E-07mmHg at 25°C
• Refractive Index: 1.619
• PKA: 3.56±0.10(Predicted)
• CAS DataBase Reference: 5-P-TOLYLPYRIMIDIN-2-YLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-P-TOLYLPYRIMIDIN-2-YLAMINE(31408-17-0)
• EPA Substance Registry System: 5-P-TOLYLPYRIMIDIN-2-YLAMINE(31408-17-0)

Safety Data

• Hazardous Substances Data: 31408-17-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-P-TOLYLPYRIMIDIN-2-YLAMINE is used as a building block for the synthesis of various biologically active molecules, including pharmaceutical drugs. Its unique structure allows it to be a key component in the development of new therapeutic agents.
Used in Antineoplastic Applications:
In the field of oncology, 5-P-TOLYLPYRIMIDIN-2-YLAMINE is studied for its potential use as an antineoplastic agent. This means it may have the ability to inhibit the growth of cancer cells, offering a new avenue for cancer treatment.
Used in Antiviral Applications:
5-P-TOLYLPYRIMIDIN-2-YLAMINE has also been investigated for its potential use as an antiviral agent, particularly against the hepatitis C virus. Its antiviral properties could contribute to the development of new treatments for viral infections.
Overall, 5-P-TOLYLPYRIMIDIN-2-YLAMINE's diverse applications in medicine, pharmaceuticals, and research highlight its importance as a versatile chemical compound with significant potential in the development of new therapeutic agents.

InChI:InChI=1/C11H11N3/c1-8-2-4-9(5-3-8)10-6-13-11(12)14-7-10/h2-7H,1H3,(H2,12,13,14)

Upstream product

• 402960-38-7 5-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)pyrimidin-2-ylamine 
• 19957-47-2 N’-(p-methylphenyl) p-toluenesulfonyl hydrazide 

Relevant articles and documents

Palladium-catalyzed Suzuki cross-coupling of N′-tosyl arylhydrazines

The first palladium-catalyzed Suzuki cross-coupling of N′-tosyl arylhydrazines with various organoboron reagents has been developed for the preparation of biaryl compounds in high yields. N′-Tosyl arylhydrazine as a readily available and stable electrophile also demonstrated its generality in a number of coupling reactions. The Royal Society of Chemistry 2013.