314082-71-8

Upstream product

• 314082-69-4 benzyl (2S,4R)-4-allyl-N-tert-butoxycarbonyl-pyrrolidine-2-carboxylate 
• 113400-36-5 benzyl (2S)-N-tert-butoxycarbonyl-5-oxoprolinate 

Downstream Products

• 941587-04-8 7(S)-1′-demethyl-7-deoxy-7-{5-(2-nitrophenyl)-1,3,4-thiadiazol-2-yl}thio-1′-N-i-propyllincomycin 
• 941585-43-9 7(S)-1′-N-(tert-butoxycarbonyl)-1′-demethyl-7-deoxy-7-{5-(2-nitrophenyl)-1,3,4-thiadiazol-2-ylthio}lincomycin 
• 941586-83-0 7(S)-1′-demethyl-7-deoxy-7-{5-(2-nitrophenyl)-1,3,4-thiadiazol-2-ylthio}lincomycin 
• 1088409-18-0 7(S)-1′-demethyl-7-deoxy-7-{4-(pyrimidin-5-yl)phenylthio}lincomycin 
• 941588-14-3 7(S)-1′-demethyl-7-deoxy-7-{4-(pyridin-3-yl)phenylthio}lincomycin 
• 1088411-03-3 7(S)-1′-N-(tert-butoxycarbonyl)-1′-demethyl-7-deoxy-7-{4-(pyrimidin-5-yl)phenylthio}lincomycin 
• 941585-41-7 7(S)-1′-N-(tert-butoxycarbonyl)-1′-demethyl-7-deoxy-7-{4-(pyridin-3-yl)phenylthio}lincomycin 
• 941587-88-8 7(S)-1′-demethyl-7-deoxy-7-{4-(morpholinocarbonyl)phenylthio}lincomycin 
• 941585-34-8 7(S)-1′-N-(tert-butoxycarbonyl)-1′-demethyl-7-deoxy-7-{4-(morpholinocarbonyl)phenylthio}lincomycin 
• 941585-32-6 7(S)-1′-N-(tert-butoxycarbonyl)-7-{4-(carboxyl)phenylthio}-1′-demethyl-7-deoxylincomycin 

Relevant academic research and scientific papers

Highly potent and selective peptide-based inhibitors of the hepatitis C virus serine protease: Towards smaller inhibitors

Structure-activity studies on a hexapeptide N-terminal cleavage product of a dodecamer substrate led to the identification of very potent and highly specific inhibitors of the HCV NS3 protease/NS4A cofactor peptide complex. The largest increase in potency