31409-32-2

Upstream product

• 116114-18-2 1-(4-Chlorobenzoyl)-4-ethylsemicarbazide 
• 536-40-3 4-chlorobenzoic acid hydrazide 
• 4426-72-6 hydrazine carboxamide 
• 109-90-0 ethyl isocyanate 

Downstream Products

• 117258-18-1 5-(4-Chloro-phenyl)-4-ethyl-2-propyl-2,4-dihydro-[1,2,4]triazol-3-one 
• 134243-98-4 1-propargyl-3-(4-chlorophenyl)-4-ethyl-1,2,4-triazolin-5-one 
• 110623-26-2 5-(4-Chlorophenyl)-4-ethyl-2-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione 
• 116114-14-8 5-(4-Chlorophenyl)-2,4-dihydro-4-ethyl-2-methyl-3H-1,2,4-triazol-3-one 
• 116114-15-9 5-(4-chlorophenyl)-2,4-dihydro-2,4-diethyl-3H-1,2,4-triazol-3-one 

Relevant academic research and scientific papers

5-aryl-3H-1,2,4-triazol-3-ones and their use in the treatment of neurodegenerative disorders

This invention relates to neuroprotective 5-aryl-3H-1,2,4-triazol-3-ones and to their use in the treatment of neurodegenerative disorders such as cerebral ischemia, stroke, Alzheimer's disease, Parkinson's disease, and Huntington's disease.

Halopropargyl compounds, compositions, uses and processes of preparation

Compounds of the formula STR1 wherein A is selected from the group consisting of hydrogen, alkyl, aryl, and heterocyclic; Y and Z are independently selected from the group consisting of O, S, and N--R; R is selected from the group consisting of hydrogen,

Fungicidal compositions and methods of use

This invention relates to the use of iodopropargyl compounds invention have the structure STR1 wherein A is hydrogen, alkyl, cycloalkyl, alkenyl, alkynyl, phenyl, phenylalkyl, naphthyl or heterocyclyl; and Z is oxygen (O) or N--R; wherein R is hydrogen, a

2,4-Dihydro-3H-1,2,4-triazol-3-ones as anticonvulsant agents

A series of 5-aryl-2,4-dihydro-3H-1,2,4-triazol-3-ones was evaluated for anticonvulsant activity. In general the members of this series were prepared by the alkaline crystalization of 1-aroyl-4-alkylsemicarbazides. The resulting 2-unsubstituted 3H-1,2,4-t

5-phenyl-3H-1,2,4-triazol-3-ones and their use as anticonvulsants

This invention relates to 5-phenyl-3H-1,2,4-triazol-3-ones and to their use as anticonvulsants for treatment of seizure disorders.

Process for the preparation of 5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones

This invention relates to a novel process for the preparation of 5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3--thiones, useful as antidepressants, through the thionation of the corresponding 5-aryl-2,4-dialkyl-3H-1,2,4-triazol--3-ones.

The Bis(tricyclohexylstannyl) Sulfide Thionation of 3H-1,2,4-Triazol-3-ones

5-Aryl-2,4-dialkyl-2,4-dihydro-3H-1,2,4-triazol-3-ones may be converted in 55-74percent yield to the corresponding 3H-1,2,4-triazole-3-thiones by using the combination bis(tricyclohexylstannyl) sulfide/boron trichloride.