314250-62-9Relevant academic research and scientific papers
Synthesis and antihepatotoxic activity of 5-(2,3-dihydro-1,4-benzodioxane- 6-yl)-3-substituted-phenyl-4,5-dihydro-1H-pyrazole derivatives
Khalilullah, Habibullah,Khan, Shamshir,Ahsan, Mohamed Jawed,Ahmed, Bahar
, p. 7251 - 7254 (2012/02/15)
In continuance of our search for newer antihepatotoxic agents some novel pyrazoline derivatives containing 1,4-dioxane ring system were synthesized starting from 3-(2,3-dihydro-1,4-benzodioxane-6-yl)-1-substituted-phenylprop-2- en-1-one. Some of the synthesized compounds were evaluated for antihepatotoxic activity against CCl4-induced hepatotoxicity in rats. Among them some compounds have shown significant antihepatotoxic activity comparable to standard drug silymarin.
