314280-47-2Relevant academic research and scientific papers
Synthetic study of aquayamycin. Part 1: Synthesis of 3-(phenylsulfonyl)phthalides possessing a β-C-olivoside
Matsumoto,Yamaguchi,Hamura,Tanabe,Kuriyama,Suzuki
, p. 8383 - 8387 (2007/10/03)
An efficient synthetic route to 3-(phenylsulfonyl)phthalides possessing a β-C-olivoside was developed by exploiting the regioselective [2+2] cycloaddition of benzyne with ketene silyl acetal. The compounds are useful in the total synthesis of the angucyclines, including aquayamycin. (C) 2000 Elsevier Science Ltd.
