314725-17-2 Usage
General Description
6-Benzofurancarboxylic acid, 4-hydroxy-2-methyl-, methyl ester, is a chemical compound belonging to the category of benzofurans. Benzofurans are organic compounds that contain a benzene ring fused to a furan ring. Being a methyl ester, this substance consists of a carboxylic acid (in this case, 6-Benzofurancarboxylic acid) in which the hydrogen of the carboxyl group is replaced by a methyl group. The 4-hydroxy-2-methyl component indicates the position of hydroxy (-OH) and methyl (-CH3) groups attached to the benzofuran core structure. The precise properties, uses, and safety information about this particular compound would be subject to additional research and information.
Check Digit Verification of cas no
The CAS Registry Mumber 314725-17-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,4,7,2 and 5 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 314725-17:
(8*3)+(7*1)+(6*4)+(5*7)+(4*2)+(3*5)+(2*1)+(1*7)=122
122 % 10 = 2
So 314725-17-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H10O4/c1-6-3-8-9(12)4-7(11(13)14-2)5-10(8)15-6/h3-5,12H,1-2H3
314725-17-2Relevant articles and documents
Sonogashira reactions with propyne: Facile synthesis of 4-Hydroxy-2-methylbenzofurans from Iodoresorcinols
Berliner, Martin A.,Cordi, Eric M.,Dunetz, Joshua R.,Price, Kristin E.
body text, p. 180 - 187 (2010/04/28)
The Sonogashira reaction of terminal alkynes and ortho-halophe- nols with subsequent cyclization is a well-precedented method for the synthesis of substituted benzofurans. Here we describe the extension of this method to the coupling of 2-iodoresorcinols and terminal alkynes, including propyne, to give 4-hydroxy-2-substi- tuted benzofurans. In particular, we describe the screening, method development, and scaleup of the reaction with propyne using standard hydrogenation equipment.
