31482-18-5

Upstream product

• 97674-02-7 tributyl(1-ethoxyvinyl)stannane 
• 159898-19-8 (9H-pyrido<3,4-b>indol-1-yl)(3-bromopyrid-4-yl)ketone 
• 154105-62-1 9-(4-Methoxy-benzyl)-1-((E)-styryl)-9H-β-carboline 
• 154105-63-2 9-(4-Methoxy-benzyl)-9H-β-carboline-1-carbaldehyde 
• 154105-66-5 4-Bromo-3-(1-methoxy-ethyl)-pyridine 
• 154105-65-4 1-(4-bromo-pyridin-3-yl)-ethanol 
• 154105-64-3 4-bromonicotinaldehyde 
• 20127-62-2 (E)-1-(2-phenylvinyl)-9H-pyrido[3,4-b]indole 
• 500-22-1 3-pyridinecarboxaldehyde 
• 159898-18-7 (9H-pyrido<3,4-b>indol-1-yl)(3-bromopyrid-4-yl)carbinol 
• 159898-15-4 1-bromo-9H-pyrido<3,4-b>indole 
• 19839-52-2 2,9-dihydro-1H-pyrido[3,4-b]indol-1-one 

Relevant academic research and scientific papers

1,9-dimetalated β-Carbolines. Versatile Building Blocks for the Total Synthesis of Alkaloids

Reactions of the dimetalated β-carboline 6, prepared from 1-bromo-β-carboline (4), with electrophiles are key steps in the syntheses of various β-carboline alkaloids.Transmetalation of 6 with ZnCl2 followed by palladium-catalyzed cross coupling reaction with 2-chloroquinoline gave the alkaloid nitramarine (14).

MAXONINE: STRUCTURE CORRECTION AND SYNTHESIS

The structure for the pentacyclic alkaloid maxonine is revised from 1 to 17.Compound 17 was prepared by total synthesis and shown identical to the natural product.