315-44-6

Basic information

• Product Name: Ethanone, 1-(2,4-dihydroxyphenyl)-2,2,2-trifluoro- (9CI)
• Synonyms: Ethanone, 1-(2,4-dihydroxyphenyl)-2,2,2-trifluoro- (9CI);2'',4''-DIHYDROXY-2,2,2-TRIFLUOROACETOPHENONE;1-(2,4-Dihydroxyphenyl)-2,2,2-trifluoroethanone;2,2,2-Trfluoro-2'2'-dihydrorlyacetophenone
• CAS NO: 315-44-6
• Molecular Formula: C₈H₅F₃O₃
• Molecular Weight: 206.1187096
• Product Categories: ACETYLHALIDE
• Mol File: 315-44-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethanone, 1-(2,4-dihydroxyphenyl)-2,2,2-trifluoro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(2,4-dihydroxyphenyl)-2,2,2-trifluoro- (9CI)(315-44-6)
• EPA Substance Registry System: Ethanone, 1-(2,4-dihydroxyphenyl)-2,2,2-trifluoro- (9CI)(315-44-6)

Safety Data

• Hazardous Substances Data: 315-44-6(Hazardous Substances Data)

Usage

General Description

Ethanone, 1-(2,4-dihydroxyphenyl)-2,2,2-trifluoro- (9CI) is a chemical compound with the molecular formula C8H5F3O3. It is also known by the name trifluoroacetylpyrocatechol. Ethanone, 1-(2,4-dihydroxyphenyl)-2,2,2-trifluoro- (9CI) is a derivative of pyrocatechol with a trifluoroacetyl group attached to the phenolic hydroxyl groups. It is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various biologically active compounds. Additionally, it has potential applications in the development of new materials and as a reagent in chemical analysis. Ethanone, 1-(2,4-dihydroxyphenyl)-2,2,2-trifluoro- (9CI) is considered to be of interest to researchers and chemists due to its unique properties and potential uses.

Upstream product

• 353-85-5 trifluoroacetonitrile 
• 108-46-3 recorcinol 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 65239-82-9 1-[2,4-Dihydroxy-3-(4-methyl-cyclohexyl)-phenyl]-2,2,2-trifluoro-ethanone 
• 65239-83-0 1-[5-(3,5-Dimethyl-cyclohexyl)-2,4-dihydroxy-phenyl]-2,2,2-trifluoro-ethanone 
• 65239-93-2 1-(3-Chloro-2,4-dihydroxy-phenyl)-2,2,2-trifluoro-ethanone 
• 65240-09-7 1-(3,5-Dichloro-2,4-dihydroxy-phenyl)-2,2,2-trifluoro-ethanone 
• 65240-11-1 1-(3,5-Dibromo-2,4-dihydroxy-phenyl)-2,2,2-trifluoro-ethanone 
• 65240-16-6 1-(2,4-Dihydroxy-5-nitro-phenyl)-2,2,2-trifluoro-ethanone 
• 65240-17-7 1-(2,4-Dihydroxy-3,5-dinitro-phenyl)-2,2,2-trifluoro-ethanone 
• 65239-74-9 1-(5-tert-Butyl-2,4-dihydroxy-phenyl)-2,2,2-trifluoro-ethanone 
• 724466-51-7 1-(2,4-dihydroxy-phenyl)-2,2,2-trifluoro-ethanone oxime 
• 843646-57-1 (2,4-dichloro-phenyl)-(6-hydroxy-3-trifluoromethyl-benzofuran-2-yl)-methanone 
• 65240-38-2 1-{5-[2,4-Dihydroxy-3-isopropyl-5-(2,2,2-trifluoro-acetyl)-benzyl]-2,4-dihydroxy-3-isopropyl-phenyl}-2,2,2-trifluoro-ethanone 
• 709028-30-8 {3-Chloro-4-[3-(3-hydroxy-2-propyl-4-{2,2,2-trifluoro-1-[(Z)-hydroxyimino]-ethyl}-phenoxy)-propylsulfanyl]-phenyl}-acetic acid methyl ester 
• 709028-29-5 (3-Chloro-4-{3-[3-hydroxy-2-propyl-4-(2,2,2-trifluoro-acetyl)-phenoxy]-propylsulfanyl}-phenyl)-acetic acid methyl ester 
• 194608-89-4 {3-chloro-4-[3-(7-propyl-3-trifluoromethyl-benzo[d]isoxazol-6-yloxy)-propylsulfanyl]-phenyl}-acetic acid methyl ester 

Relevant articles and documents

Biocatalytic Properties and Structural Analysis of Phloroglucinol Reductases

Phloroglucinol reductases (PGRs) are involved in anaerobic degradation in bacteria, in which they catalyze the dearomatization of phloroglucinol into dihydrophloroglucinol. We identified three PGRs, from different bacterial species, that are members of the family of NAD(P)H-dependent short-chain dehydrogenases/reductases (SDRs). In addition to catalyzing the reduction of the physiological substrate, the three enzymes exhibit activity towards 2,4,6-trihydroxybenzaldehyde, 2,4,6-trihydroxyacetophenone, and methyl 2,4,6-trihydroxybenzoate. Structural elucidation of PGRcl and comparison to known SDRs revealed a high degree of conservation. Several amino acid positions were identified as being conserved within the PGR subfamily and might be involved in substrate differentiation. The results enable the enzymatic dearomatization of monoaromatic phenol derivatives and provide insight into the functional diversity that may be found in families of enzymes displaying a high degree of structural homology.