31505-42-7Relevant articles and documents
Monophosphate A conjugated-Tn anti-tumor vaccine and application thereof
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Paragraph 0052; 0054-0056, (2019/09/17)
The invention provides a monophosphate A conjugated-Tn anti-tumor vaccine. The monophosphate A conjugated-Tn anti-tumor vaccine is a compound shown in a formula (I), namely Y-L-X(I). The monophosphateA conjugated-Tn anti-tumor vaccine is characterized in that a compound of the second generation of TLR4 ligand I of wholly new structure in the formula (I) is used for replacing MPLA (modified polylactic acid) and coupling with a compound (Tn) with clinical development potential in a formula (II), so as to obtain the two-component vaccine with a clear structure and a stronger anti-tumor function;the anti-tumor application prospect is better.
ANTIBODY CONJUGATES AND METHODS OF MAKING THE ANTIBODY CONJUGATES
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Paragraph 0191, (2017/01/02)
Described herein are antibody conjugates and methods of making antibody conjugates.
THE PHTHALATION OF 2-AMINO-2-DEOXY-D-GLUCOSE AND N-METHYL-1-AMINO-1-DEOXY-D-GLUCITOL; CONVERSION OF THE PRODUCTS TO ORGANOTIN DERIVATIVES. A READY MIGRATION OF ACETYL FROM OXYGEN TO NITROGEN UNDER NEUTRAL CONDITIONS
Patel, Atula,Poller, Robert C.
, p. 182 - 184 (2007/10/02)
N-Phthalation of 3-amino-3-deoxy-D-glucose was followed by replacement of the acidic proton by tributyl- and triphenylstannyl groups.A similar reaction with 1-(methylamino)-1-deoxy-D-glucitol failed and successive treatment with benzyl chloroformate and acetic anhydride followed by catalytic hydrogenation showed that a 1,4-O->N acetyl migration had occured.Phthalation and stannylation succeeded under different conditions.