31520-37-3

Upstream product

• 103-72-0 phenyl isothiocyanate 
• 31911-99-6 Benzyl-[1,3]thiazepan-(2Z)-ylidene-amine 
• 200337-28-6 N,N-Dimethyl-N'-[1,3]thiazepan-(2Z)-ylidene-benzene-1,4-diamine 
• 73377-38-5 5,6,8,9-tetrahydro-7-phenyldibenzoxanthyilium triflouromethanesulphonate 
• 80254-32-6 N'-(4-aminobutyl)-N-phenylthiourea 
• 31520-32-8 1-bromo-4-isothiocyanato-butane 
• 62-53-3 aniline 

Relevant academic research and scientific papers

1,3-Thiazepines. 2. Reaction of 2-iminohexahydrothiazepines with phenylisocyanate and isothiocyanates

We have shown that as a result of reaction of phenylisocyanate with 2-benzyl- and 2-aryliminohexahydrothiazepines, the corresponding N-substituted N-tetrahydroazepinyl-N′-phenylureas are formed. In the case of isothiocyanates, on boiling in different solvents we obtained the products of the exchange reaction; and at room temperature, we also obtained substituted thioureas. We suggest a probable scheme for the process. 1997 Plenum Publishing Corporation.

1,3-Thiazepines. 1. Synthesis and spectral properties of 2-iminohexahydro-1,3-thiazepines

By reaction of 4-amino-1-butanol with isothiocyanates RNCS, we have synthesized N-(4-hydroxybutyl)-N′-R-thioureas, which by cyclization when treated with hydrohalic acids are converted to the corresponding 2-(R)-imino)hexahydro-1,3-thiazepines. The structure of the compounds obtained has been confirmed by PMR, IR, and mass spectra. 1997 Plenum Publishing Corporation.

TRANSFORMATIONS OF PYRIDINIUMS DERIVED FROM AMINO-ALCOHOLS AND FROM DIAMINES

Pyridiniums derived from amino alcohols cyclise to ethers or rearrange to aldehydes on heating.Monopyridiniums from diamines can be acylated or converted into ureas or thioureas: these products cyclise on heating in solution to give dihydro-thiazoles, -4H-thiazines, -oxazoles, -4H-oxazines, or tetrahydro-3H-thiazepines.