315239-28-2

Usage

Type of compound

quinazolinone derivative

Contains

a propynylsulfanyl group

Potential pharmacological properties

antimicrobial, anticancer

Investigated as a therapeutic agent for

various diseases, including inflammatory and neurological disorders

Significance of propynylsulfanyl group

may contribute to biological activities

Target for

further research and development in the pharmaceutical industry

Upstream product

• 13906-09-7 2-thioxo-2,3-dihydro-1H-quinazolin-4-one 
• 106-96-7 propargyl bromide 
• 80882-73-1 2-mercapto-4(1H)-quinazolinone potassium salt 

Downstream Products

• 1287685-91-9 1-(4-nitrobenzyl)-5H-[1,3]thiazolo[3,2-a]quinazolin-5-one 
• 1287686-04-7 1-(3-chloro-4-cyanobenzyl)-5H-[1,3]thiazolo[3,2-a]quinazolin-5-one 
• 1287685-89-5 1-(3-nitrobenzyl)-5H-[1,3]thiazolo[3,2-a]quinazolin-5-one 
• 1287686-00-3 1-(4-chloro-2-nitrobenzyl)-5H-[1,3]thiazolo[3,2-a]quinazolin-5-one 
• 1287685-93-1 1-(4-cyanobenzyl)-5H-[1,3]thiazolo[3,2-a]quinazolin-5-one 
• 1287685-87-3 1-(2-nitrobenzyl)-5H-[1,3]thiazolo[3,2-a]quinazolin-5-one 
• 1287685-95-3 1-(2-methyl-4-nitrobenzyl)-5H-[1,3]thiazolo[3,2-a]quinazolin-5-one 
• 1287685-98-6 1-(2-chloro-4-nitrobenzyl)-5H-[1,3]thiazolo[3,2-a]quinazolin-5-one 
• 1287686-02-5 1-(3-chloro-4-nitrobenzyl)-5H-[1,3]thiazolo[3,2-a]quinazolin-5-one 

Relevant academic research and scientific papers

Heterocyclization reactions of 2-(2-propynylthio)-4(1H)-quinazolinone derivatives when treated with electrophilic and nucleophilic reagents

Reaction of the potassium salt of 2-thioquinazolin-4-one with propargyl halides leads to formation of 2-propargylthioquinazolin-4-one derivatives, which undergo heterocyclization when they are treated with electrophilic or nucleophilic reagents and, depen

Regioselective syntheses of 1-aryl-substituted-5H-[1,3]thiazolo[3,2-a] quinazoline-5-ones during sonogashira coupling

Reaction of 2-mercaptopropargylquinazoline-4-one with various aryliodides catalyzed by Pd-Cu leads to the regioselective formation of 1-arylsubstituted- 5H-[1,3]thiazolo-[3,2-a]quinazoline-5-ones. Copyright Taylor & Francis Group, LLC.