31526-43-9

Basic information

• Product Name: 5-ethoxy-1-(4-methoxyphenyl)pentan-1-one
• CAS NO: 31526-43-9
• Molecular Weight: 236.311
• Mol File: 31526-43-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-ethoxy-1-(4-methoxyphenyl)pentan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-ethoxy-1-(4-methoxyphenyl)pentan-1-one(31526-43-9)
• EPA Substance Registry System: 5-ethoxy-1-(4-methoxyphenyl)pentan-1-one(31526-43-9)

Safety Data

• Hazardous Substances Data: 31526-43-9(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 154477-03-9 5-(4'-methoxyphenyl)-4-pentyn-1-ol 
• 25305-58-2 ethyl 5-(4-methoxyphenyl)-5-oxopentanoate 
• 25882-27-3 5-hydroxy-1-(4-methoxyphenyl)pentan-1-one 
• 25882-26-2 4-p-Anisoylbutyl-toluol-p-sulfonat 

Relevant articles and documents

p-Toluenesulfonic acid-promoted selective functionalization of unsymmetrical arylalkynes: a regioselective access to various arylketones and heterocycles

Regioselective hydration of a wide range of internal alkynes has been afforded in high to good yields by using PTSA in EtOH. The scope of the reaction of alkynes has been delineated. Arylaliphatic alkynes and diarylalkynes were regioselectively hydrated in good to excellent yields and short reaction times when the reaction was achieved under microwave irradiation. Moreover, diarylalkynes, arylenynes as well as diaryldiynes bearing a methoxy- or a thiomethyl substituent on the ortho position underwent a regioselective 5-endo-dig-cyclization to give a variety of 2-aryl- and 2-styrylbenzofuran or benzothiphene derivatives. We believe that, this new environmentally metal-free procedure combined to microwave irradiation would be in importance in the search of green laboratory-scale synthesis.