3153-01-3

Usage

Uses

Used in Pharmaceutical Industry:
2,3,5,6-Tetrafluoro-4-methoxybenzoic acid is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to enhance the stability and efficacy of drug molecules.
Used in Agrochemical Industry:
In the agrochemical sector, 2,3,5,6-tetrafluoro-4-methoxybenzoic acid is utilized as a building block for the development of agrochemicals, contributing to the creation of compounds with improved performance and environmental compatibility.
Used in Organic Chemistry:
2,3,5,6-Tetrafluoro-4-methoxybenzoic acid is employed as a versatile building block in organic chemistry for the synthesis of complex molecules, leveraging its unique fluorinated structure to achieve specific chemical properties and reactivity.
Used in Fluorinated Compounds Production:
2,3,5,6-TETRAFLUORO-4-METHOXYBENZOIC ACID is used as an intermediate in the production of other fluorinated compounds, capitalizing on its high fluorination to impart desirable characteristics such as chemical stability and resistance to degradation in various applications.

Upstream product

• 131684-02-1 2-(2,3,4,5-tetrafluoro-6-methoxyphenyl)-4,4-dimethyl-2-oxazoline 
• 14865-77-1 p-CH₃OC₆F₄C₂C₆F₄OCH₃ 
• 13557-43-2 1,2-bis(pentafluorophenyl)acetylene 
• 602-94-8 Pentafluorobenzoic acid 

Downstream Products

• 17490-79-8 methyl 2,3,5,6-tetrafluoro-4-methoxy benzoate 

Relevant academic research and scientific papers

Synthesis and biological activity of 5-amino- and 5-hydroxyquinolones, and the overwhelming influence of the remote N1-substituent in determining the structure-activity relationship

A series of 5-amino- and 5-hydroxyquinolone antibacterials substituted at C7 with a select group of common piperazinyl and 3-aminopyrrolidinyl side chains was prepared. These 5-substituted derivatives were compared to the analogous 5-hydrogen compounds for antiinfective activity by using DNA gyrase inhibition, minimum inhibitory concentrations against a variety of bacteria, and in vivo efficacy in the mouse infection model. The influence on the structure-activity relationships of varied substituents at C8 (H, F, Cl) and N1 (ethyl, cyclopropyl, difluorophenyl) was also studied. The results showed that several of the structure-activity conclusions regarding side-chain bulk at C7, the effect of halogen at C8, and the effect of the C5-amino group were greatly influenced by the choice of the N1-substituent. Several outstanding broad spectrum quinolones were identified in this work. In particular, the spectrum and potency of the 7-piperazinyl quinolones could be greatly enhanced by the judicious choice of C5-, C8-, and N1-substitutents.

Halogenated esters

Compounds of formula (I), useful as insecticides and knockdown agents: STR1 where Y is C1-6 alkoxy, Z is halo or C1-6 alkoxy; R is --(CH2)p --(O)m --R3 where m and p may be 0 or 1; R3