3153-72-8Relevant academic research and scientific papers
Synthesis of biaryls by Pd-catalyzed decarboxylative homo- and heterocoupling of substituted benzoic acids
Xie, Kai,Wang, Sizhuo,Yang, Zhiyong,Liu, Jidan,Wang, Anwei,Li, Xiujian,Tan, Ze,Guo, Can-Cheng,Deng, Wei
supporting information; experimental part, p. 5787 - 5790 (2011/11/06)
By carefully choosing the right substrate ratio, catalyst combination, and base, symmetrical and unsymmetrical biaryls can be readily synthesized through the Pd-catalyzed decarboxylative homo- and heterocoupling of substituted benzoic acids. The reaction gave the desired products in 40-90% yield and is compatible with 2-nitro-, 2-methoxy-, 2-fluoro-, and 2-chloro-substituted benzoic acids. With the correct substrate ratio, catalyst combination, and base, symmetrical and unsymmetrical biaryls can be readily synthesized through the Pd-catalyzed decarboxylative homo- and heterocoupling of substituted benzoic acids.
Thieme journal awardees - Where are they now? on cobalt-catalyzed biaryl coupling reactions
Mayer, Matthias,Czaplik, Waldemar Maximilian,Jacobi Von Wangelin, Axel
experimental part, p. 2919 - 2923 (2010/01/21)
An operationally simple biaryl coupling reaction has been developed. The underlying domino process involves in situ Grignard formation from aryl bromides and subsequent homocoupling with catalytic CoCl2 and 1 bar synthetic air as terminal oxidant. Georg Thieme Verlag Stuttgart.
Palladium-catalyzed cross-coupling of organolead compounds with hypervalent iodonium salts
Kang, Suk-Ku,Choi, Sang-Chul,Baik, Tae-Gon
, p. 2493 - 2499 (2007/10/03)
The palladium-catalyzed cross-coupling of hypervalent iodonium salts with organolead triacetates was achieved with Pd2(dba)3 · CHCl3 (5 mol %) in the presence of NaOMe (2 equiv) in CHCl3 at room temperature.
Preparation of 7-oxaaporphine derivatives and evaluation of their dopaminergic activity
Banzatti,Carfagna,Commisso,Heidempergher,Pegrassi,Melloni
, p. 1466 - 1471 (2007/10/02)
A series of 7-oxaaporphine derivatives was prepared. The compounds were evaluated as dopaminergic agents. None of them showed either affinity for dopamine receptors or activity in vivo in the climbing behavior (mice) and turning behavior (6-hydroxydopamin
Nickel-Catalyzed Synthesis of Arylacetonitriles from Arylzinc Chlorides and Bromoacetonitrile
Frejd, Torbjoern,Klingstedt, Tomas
, p. 40 - 42 (2007/10/02)
Arylacetonitriles are synthesised by coupling arylzinc chlorides with bromoacetonitrile using Ni(acac)2/P(c-C6H11)(C6H5)2 as catalyst.The arylacetonitriles are reduced in situ with LiAlH4/AlCl3 to give the corresponding 2-aryl-1-aminoethanes.
