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2,4-dimethoxy-5-iodobenzoic acid is a chemical compound that belongs to the class of benzoic acids. It is a derivative of benzoic acid with two methoxy groups and an iodine atom attached to the benzene ring. This unique structure endows it with versatile chemical properties, making it a valuable intermediate in various chemical and pharmaceutical applications.

3153-77-3

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3153-77-3 Usage

Uses

Used in Organic Synthesis:
2,4-dimethoxy-5-iodobenzoic acid is used as a building block in organic synthesis for the creation of complex organic molecules. Its reactivity and structural features facilitate the synthesis of a wide range of compounds, contributing to the development of new chemical entities.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2,4-dimethoxy-5-iodobenzoic acid is utilized as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in the Development of New Materials:
2,4-dimethoxy-5-iodobenzoic acid is also used in the development of new materials due to its versatile chemical properties. Its potential applications in material science include the creation of novel polymers, coatings, and other advanced materials with specific properties.
Used in the Development of Biologically Active Compounds:
Due to its unique structure and reactivity, 2,4-dimethoxy-5-iodobenzoic acid has potential applications in the development of biologically active compounds. It can be used to synthesize new compounds with potential applications in medicine, agriculture, and other fields where bioactive substances are required.

Check Digit Verification of cas no

The CAS Registry Mumber 3153-77-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,1,5 and 3 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 3153-77:
(6*3)+(5*1)+(4*5)+(3*3)+(2*7)+(1*7)=73
73 % 10 = 3
So 3153-77-3 is a valid CAS Registry Number.

3153-77-3Upstream product

3153-77-3Downstream Products

3153-77-3Relevant academic research and scientific papers

Silver(I)-catalyzed iodination of arenes: Tuning the lewis acidity of N-iodosuccinimide activation

Racys, Daugirdas T.,Sharif, Salaheddin A. I.,Pimlott, Sally L.,Sutherland, Andrew

, p. 772 - 780 (2016)

A mild and rapid method for the iodination of arenes that utilizes silver(I) triflimide as a catalyst for activation of N-iodosuccinimide has been developed. The transformation was found to be general for a wide range of anisole, aniline, acetanilide, and phenol derivatives and allowed the late-stage iodination of biologically active compounds such as PIMBA, a SPECT imaging agent of breast cancer, and (a?)-IBZM, a dopamine D2 receptor antagonist. The method was also modified for the radioiodination of arenes using a one-pot procedure involving the in situ generation of [125I]-N-iodosuccinimide followed by the silver(I)-catalyzed iodination.

Highly Regioselective Iodination of Arenes via Iron(III)-Catalyzed Activation of N-Iodosuccinimide

Racys, Daugirdas T.,Warrilow, Catherine E.,Pimlott, Sally L.,Sutherland, Andrew

supporting information, p. 4782 - 4785 (2015/10/12)

An iron(III)-catalyzed method for the rapid and highly regioselective iodination of arenes has been developed. Use of the powerful Lewis acid, iron(III) triflimide, generated in situ from iron(III) chloride and a readily available triflimide-based ionic liquid allowed activation of N-iodosuccinimide (NIS) and efficient iodination under mild conditions of a wide range of substrates including biologically active compounds and molecular imaging agents.

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