3155-71-3Relevant articles and documents
Wuersch,Schwieter
, p. 1067,1069 (1956)
Preparation method of 2-methyl-4-(2, 6, 6-trimethylcyclohexene-1-yl)-2-butenal
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, (2020/08/18)
The invention provides a preparation method of 2-methyl-4-(2, 6, 6-trimethylcyclohexene-1-yl)-2-butenal. According to the method, 2-methyl-4-halogenated-2-butenal acetal is used as a raw material andreacts with magnesium powder, triphenylphosphine or triphosphite to obtain a corresponding Grignard reagent or Wittig compound, then the Grignard reagent or Wittig compound reacts with 2, 2, 6-trimethylcyclohexanone, and finally a target product is obtained through a deprotection reaction under the acidic condition. The obtained 2-methyl-4-(2, 6, 6-trimethylcyclohexene-1-yl)-2-butenal can be usedas a key intermediate to prepare vitamin A acetate. The method has the advantages of cheap and easily available raw materials, easy realization and control of reaction conditions, safe operation, greenness, environmental protection and low cost. The reaction atom economy is high, the target product yield and purity are high, impurities are few, and the method is suitable for industrial green production.
Environment-friendly synthesis process for preparing tetradecanal from epoxy carboxylate ester
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Paragraph 0003; 0020, (2017/06/02)
The invention relates to an environment-friendly synthesis process for preparing tetradecanal from epoxy carboxylate ester. The process comprises steps as follows: (1) a methanol solution of epoxy carboxylate ester is pre-cooled to a certain temperature, a proper quantity of water solutions of A are added, and the mixture reacts for a period of time; (2) the reaction mixture is filtered, and solid salt and a methanol solution of tetradecanal are obtained; (3) the solid salt is washed with methanol until no organic matters are left, and then is dried; (4) sufficient acidic gas B is introduced to the methanol solution of tetradecanal until the methanol solution of tetradecanal becomes weakly alkaline, a little produced solid salt is filtered and treated together with the solid salt in the step (3), the methanol solution of tetradecanal is subjected to solvent removal, and a crude product of tetradecanal is obtained. Emission of high-COD wastewater is avoided, the use quantity of organic solvents is reduced, and the good environment-friendly value is realized; meanwhile, extraction, evaporation or distillation of the wastewater is reduced, and energy consumption is reduced; besides, without discharge of wastewater, the tetradecanal product is basically not lost, and the reaction yield is also improved.