3156-45-4

Upstream product

• 75-52-5 nitromethane 
• 105-07-7 4-cyanobenzaldehyde 
• 563-70-2 bromonitromethane 

Downstream Products

• 76590-50-6 2-(4-cyanophenyl)-2-oxoacetic acid 

Relevant academic research and scientific papers

Polymeric nanoassembly of imine functionalized magnetite for loading copper salts to catalyze Henry and A3-coupling reactions

Poly(ethylenimine) was grafted on the magnetite (Fe3O4) nanoparticles, and subsequently reacted with different aldehydes to form the imine functionalities (Fe3O4-Imine NPs). Thus formed Fe3O4/su

Method for preparing 2-nitroalkyl-1-alcohol compound and application thereof

The invention relates to a method for preparing a 2-nitroalkane-1-alcohol compound and application thereof, and particularly provides a method for preparing the 2-nitroalkane-1-alcohol compound from iron powder/lead dichloride. The process has the advantages of good yield, high diastereoselectivity, wide functional group tolerance and good compatibility.

A urea-containing metal-organic framework as a multifunctional heterogeneous hydrogen bond-donating catalyst

A urea-containing metal-organic framework (MOF) was synthesized from a V-shaped dicarboxylate ligand and Cu(II) ions. As the undesirable self-aggregation of the urea moiety has been prohibited in the framework, this MOF can act as a heterogeneous hydrogen

Base-catalyzed reactions enhanced by solid acids: Amine-catalyzed nitroaldol (Henry) reactions enhanced by silica gel or mesoporous silica SBA-15

The reactions of various aldehydes with CH3NO2 catalyzed by Et3N, n-C6H13NH2, and Me2N(CH2)2NH2 were accelerated by the addition of silica gel to give aromatic (aliphatic) β-nitroalcohols, aromatic nitroalkenes, and aromatic 1,3-dinitroalkanes, respectively. Mesoporous silica SBA-15 showed higher activity than silica gel for the synthesis of aromatic nitroalkenes by the reactions of the corresponding aldehydes with CH3NO2 catalyzed by n-C6H13NH2.

Bottom-Up Assembly of a Highly Efficient Metal-Organic Framework for Cooperative Catalysis

In this study, we demonstrate a bottom-up assembly of a monomeric copper complex and a two-dimensional (2-D) heterometallic metal-organic framework (MOF) from a carboxylate-functionalized tridentate Schiff base ligand and metal ions. The obtained 2-D MOF

A double-chiral amino alcohol compound and its preparation method and application

The invention discloses a bis-chiral alkamine compound and a preparation method therefor and application thereof. A chiral ligand is selected and synthesized to prepare a chiral catalyst. The chemical name of the compound is N,N'-bis[(1S)-2-hydroxyl-1-ary

Catalytic Macroporous Biohydrogels Made of Ferritin-Encapsulated Gold Nanoparticles

Reported is a modular approach for the incorporation and stabilization of gold nanoparticles inside a three-dimensional macroporous hydrogel made of ferritin. The strategy, which involves the dynamic templating of surfactant H1 domains, deminer

Microporous polyurethane material for size selective heterogeneous catalysis of the Knoevenagel reaction

The first polyurethane material which is microporous (BET surface area of 312 m2 g-1) is prepared by solvothermal synthesis and acts as highly efficient and recyclable heterogeneous catalyst in the Knoevenagel condensation showing si

Application of natural feedstock extract: The Henry reaction

For the first time, we have successfully performed the Henry reaction in neat 'Natural Feedstock Extract' at room temperature. Herein, we used two most abundant natural feedstock extracts such as 'Water Extract of Banana' (WEB) and 'Water Extract of Rice Straw Ash' (WERSA). This protocol is highly advantageous owing to the employment of natural feedstock as green reaction media resulting in significant novelty and advancement with respect to green and sustainable chemistry.

Silver comes into play: Henry reaction and domino cycloisomerisation sequence catalysed by [Ag(i)(Pc-L)] complexes

We report herein the synthesis of new pyridine-containing macrocyclic ligands (Pc-L) bearing a non-innocent pendant arm, by exploiting both chiral and functional properties of natural amino acids. The obtained macrocyclic ligands were employed to synthesize well-defined cationic silver(i) complexes that were shown to be competent catalysts for the Henry (nitroaldol) reaction. Good to excellent yields and full selectivity in the β-nitroalcohol product were obtained starting from electron-poor aromatic aldehydes or other activated aldehydes such as furfural under mild reaction conditions. The straightforward synthesis of the macrocyclic ligands starting from cheap commercially available starting materials allowed the introduction of a suitable basic functionality into the ligand pendant arm, thus providing a bifunctional catalyst. Based on our previous experience in the [Ag(i)(Pc-L)] catalysed domino addition/cycloisomerisation reaction of o-alkynylbenzaldehydes and nucleophiles, the synthesis of isochromenes coupling the Henry reaction and the cycloisomerisation in a single step was subsequently explored. Although with low selectivity, [Ag(i)(Pc-L)] cationic complexes were able to promote such a cascade reaction and a possible mechanism based on experimental evidence has been proposed.