315663-76-4Relevant academic research and scientific papers
Access to new cytotoxic bisindole alkaloids by a modified Borch reductive amination process
Lewin, Guy,Schaeffer, Corinne,Hocquemiller, Reynald,Jacoby, Edgar,Leonce, Stephane,Pierre, Alain,Atassi, Ghanem
, p. 2353 - 2356 (2000)
A slight modification of the Borch reductive amination method (delayed addition of NaBH3CN) was applied to an indole aldehyde compound, analog of the natural alkaloid, goniomitine. This reaction led to a series of new cytotoxic bisindole alkaloids with a 1,2,3,4-tetrahydroquinoline bridge.
