315706-45-7Relevant academic research and scientific papers
Zinc metal-promoted cross-coupling reaction of non-activated alkyl halides with aldehydes in the presence of chlorotrimethylsilane
Ito, Takatoshi,Ishino, Yoshio,Mizuno, Takumi,Ishikawa, Akira,Kobayashi, Jun-Ichi
, p. 2116 - 2118 (2007/10/03)
Treatment of non-activated alkyl halides 1 with aldehydes 3 in the presence of zinc metal and chlorotrimethylsilane (TMSC1), DMA and/or NMP in THF brought about highly facile and effective cross-coupling to give the corresponding alcohols in good yield. These reactions are assumed to proceed through zinc reagent intermediates generated in situ.
Distant functionalization via incorporation of thiophene moieties in electrophilic reactions promoted by samarium diiodide
Yang, Shyh-Ming,Nandy, Sandip Kumar,Selvakumar, Anandakathir Robinson,Fang, Jim-Min
, p. 3719 - 3721 (2007/10/03)
(matrix presented) Methyl thiophene-2-carboxylate, methyl 3-(thien-2-yl)acrylate, and methyl 5,2′-bithiophene-2-carboxylate were utilized as the synthetic equivalents of pentanoate 5-anion, pentanoate 4,5-dianion, heptanoate 7-anion, and nonanoate-8,9-dia
