315712-37-9Relevant articles and documents
UFU ('Ullmann-Finkelstein-Ullmann'): a new multicomponent reaction
Toto, Patrick,Gesquière, Jean-Claude,Cousaert, Nicolas,Deprez, Benoit,Willand, Nicolas
, p. 4973 - 4978 (2006)
We developed conditions to carry out the first 'one-pot' Ullmann-Finkelstein-Ullmann multicomponent reaction reported. This reaction allows the one-pot synthesis of dissymmetrical para-disubstituted benzene scaffold from 1-bromo-4-iodobenzene and two N-nu
Method for synthesizing amide derivative under catalysis of vanadium
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Paragraph 0013-0015; 0043-0045, (2021/02/10)
The invention discloses a method for synthesizing an amide derivative under the catalysis of vanadium, which comprises the following step of: by using a nitro aromatic compound and an ester compound as raw materials, a vanadium compound as a catalyst and magnesium chips as a reducing agent, carrying out amidation reaction in an organic solvent to obtain the amide derivative. The method has the advantages that (1) the nitro aromatic compound which is good in stability, low in price and easy to obtain is used as a nitrogen source; (2) the used catalyst is cheap, easy to obtain and low in toxicity; and (3) the method has good substrate applicability, and is suitable for aromatic nitro compounds, fatty esters and aryl esters containing different substituents.