315717-76-1

Basic information

• Product Name: 3-Aminomethyl-1-N-Cbz-piperidine
• Synonyms: BENZYL 3-(AMINOMETHYL)PIPERIDINE-1-CARBOXYLATE;3-(AMINOMETHYL)PIPERIDINE, N1-CBZ PROTECTED;3-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER;3-AMINOMETHYL-1-N-CBZ-PIPERIDINE;N-CBZ-3-AMINOMETHYLPIPERIDINE;3-(Aminomethyl)piperidine, N1-CBZ protected 97%;1-Piperidinecarboxylic acid, 3-(aminomethyl)-, phenylmethyl ester;benzyl 3-(aminomethyl)piperidine-1-carboxylate(SALTDATA: FREE)
• CAS NO: 315717-76-1
• Molecular Formula: C₁₄H₂₀N₂O₂
• Molecular Weight: 248.3208
• Product Categories: Aminomethyl's;Pyrans, Piperidines &Piperazines;Pyrans, Piperidines & Piperazines
• Mol File: 315717-76-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 385.7 °C at 760 mmHg
• Flash Point: 187.1 °C
• Appearance: /
• Density: 1.125 g/cm³
• Vapor Pressure: 3.73E-06mmHg at 25°C
• Refractive Index: 1.55
• Storage Temp.: 2-8°C(protect from light)
• PKA: 10.12±0.29(Predicted)
• CAS DataBase Reference: 3-Aminomethyl-1-N-Cbz-piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Aminomethyl-1-N-Cbz-piperidine(315717-76-1)
• EPA Substance Registry System: 3-Aminomethyl-1-N-Cbz-piperidine(315717-76-1)

Safety Data

• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 315717-76-1(Hazardous Substances Data)

Usage

General Description

3-Aminomethyl-1-N-Cbz-piperidine is a chemical compound with the molecular formula C17H23N3O2. It is a piperidine derivative with an amine group and a carboxybenzyl (Cbz) protecting group. 3-Aminomethyl-1-N-Cbz-piperidine is commonly used in organic synthesis as a building block for the preparation of various pharmaceuticals and biologically active molecules. It is also known for its potential use as a reagent in the synthesis of peptide-based drugs. Additionally, 3-Aminomethyl-1-N-Cbz-piperidine has been studied for its pharmacological properties, including its role as a potential inhibitor of certain enzymes and receptors. Overall, this compound has diverse applications in the chemical and pharmaceutical industries.

InChI:InChI=1/C14H20N2O2/c15-9-13-7-4-8-16(10-13)14(17)18-11-12-5-2-1-3-6-12/h1-3,5-6,13H,4,7-11,15H2

Downstream Products

• 683269-44-5 3-{[(2,3-dihydro-benzo[1,4]dioxin-6-ylmethyl)amino]-methyl}-piperidin-1-ylcarboxylic acid benzyl ester 
• 1262294-04-1 benzyl 3-((6-chloro-4-iodopyridin-2-ylamino)methyl)piperidine-1-carboxylate 
• 1198306-40-9 ethyl 4-((1-(benzyloxycarbonyl)piperidin-3-yl)methylamino)-2-chloropyrimidine-5-carboxylate 
• 220031-84-5 3-[(tert-butoxycarbonylamino)methyl]-piperidin-1-ylcarboxylic acid benzyl ester 

Relevant articles and documents

Disubstituted pyrimidines as Lck inhibitors

We have developed a family of 4-benzimidazolyl-N-piperazinethyl-pyrimidin-2-amines that are subnanomolar inhibitors of Lck. A subset of these Lck inhibitors, with heterocyclic substituents at the benzimidazole C5, are also low-nanomolar inhibitors of cell

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Pyrimidine compounds (Formula I), or their pharmaceutically acceptable salts, hydrates, solvates, crystal forms and individual diastereomers, and pharmaceutical compositions including the same, which are inhibitors of tyrosine kinase enzymes, and as such are useful in the prophylaxis and treatment of proteins tyrosine kinase-associated disorders, such as immune diseases, hyperproliferative disorders and other diseases in which inappropriate protein kinase action is believed to play a role, such as cancer, angiogensis, atheroscelerosis, graft rejection, rheumatoid arthritis and psoriasis.