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3-[[2-[2,4-bis(tert-pentyl)phenoxy]butyryl]amino]-N-[4,5-dihydro-5-oxo-1-(2,4,6-trichlorophenyl)-1H-pyrazol-3-yl]benzamide, commonly referred to as TAK-220, is a complex chemical compound with significant pharmaceutical potential. It is characterized by its unique molecular structure, which includes 2,4-bis(tert-pentyl)phenoxy and 2,4,6-trichlorophenyl groups, and functions as a selective antagonist of the chemokine receptor CCR5. This receptor is integral to inflammatory responses and immune system regulation, making TAK-220 a promising candidate for therapeutic intervention in various diseases.

31598-52-4

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31598-52-4 Usage

Uses

Used in Pharmaceutical Industry:
TAK-220 is used as a therapeutic agent for the treatment of HIV due to its ability to inhibit the CCR5 receptor, which is utilized by HIV to enter host cells. By blocking this receptor, TAK-220 can potentially prevent viral entry and replication, offering a novel approach to managing the disease.
Used in Inflammatory Disease Treatment:
In the field of immunology, TAK-220 is utilized as an anti-inflammatory agent. Its antagonistic effect on the CCR5 receptor can help modulate the immune response and reduce inflammation associated with various inflammatory diseases, thereby providing relief and potentially altering the progression of such conditions.
Used in Research Applications:
TAK-220 also serves as a valuable research tool in the study of the CCR5 receptor's role in immune function and disease progression. It aids scientists in understanding the mechanisms of action and potential therapeutic targets within the immune system, which can lead to the development of new treatments for a range of conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 31598-52-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,5,9 and 8 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 31598-52:
(7*3)+(6*1)+(5*5)+(4*9)+(3*8)+(2*5)+(1*2)=124
124 % 10 = 4
So 31598-52-4 is a valid CAS Registry Number.
InChI:InChI=1/C36H41Cl3N4O4/c1-8-28(47-29-15-14-22(35(4,5)9-2)17-25(29)36(6,7)10-3)34(46)40-24-13-11-12-21(16-24)33(45)41-30-20-31(44)43(42-30)32-26(38)18-23(37)19-27(32)39/h11-19,28H,8-10,20H2,1-7H3,(H,40,46)(H,41,42,45)

31598-52-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-[2-[2,4-bis(2-methylbutan-2-yl)phenoxy]butanoylamino]-N-[5-oxo-1-(2,4,6-trichlorophenyl)-4H-pyrazol-3-yl]benzamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:31598-52-4 SDS

31598-52-4Upstream product

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