Welcome to LookChem.com Sign In|Join Free
  • or
5-fluoro-6-methoxy-8-nitroquinoline is a synthetic organic compound characterized by the presence of a quinoline ring, which is a tricyclic aromatic system. This particular compound features a fluorine atom at the 5-position, a methoxy group (-OCH3) at the 6-position, and a nitro group (-NO2) at the 8-position. The combination of these functional groups gives the molecule distinct chemical properties, such as potential reactivity and stability, which can be influenced by the electron-withdrawing or electron-donating nature of the substituents. 5-fluoro-6-methoxy-8-nitroquinoline may be of interest in medicinal chemistry or material science due to its unique structure and the possibility of it exhibiting specific biological activities or physical properties. However, without further context or application, it's challenging to provide a more detailed summary of its uses or significance.

316-77-8

Post Buying Request

316-77-8 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

316-77-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 316-77-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,1 and 6 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 316-77:
(5*3)+(4*1)+(3*6)+(2*7)+(1*7)=58
58 % 10 = 8
So 316-77-8 is a valid CAS Registry Number.

316-77-8Relevant academic research and scientific papers

Synthesis of the 8-aminoquinoline antimalarial 5-fluoroprimaquine

O'Neill, Paul M.,Storr, Richard C.,Park, B. Kevin

, p. 4615 - 4622 (1998)

Several approaches to the synthesis of 5-fluoro-6-methoxy-8- nitroquinoline 5, the key intermediate required for the synthesis of 5- fluoroprimaquine, were investigated. In one approach, 5chloro-6-methoxy-8- nitroquinoline was synthesised and treated with a variety of nucleophilic sources of fluoride. In another approach, electrophilic substitution of 6- methoxy-8-nitroquinoline with (N-fluorosulfonimide, NFSI) was investigated. The final approach to 5 involved a modified Skraup reaction of 5-fluoro-4- methoxy-2-nitroaniline which gave the required intermediate in 30% yield.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 316-77-8