316125-27-6

Basic information

• Product Name: 2-(4-chlorophenyl)-4-(4-methylpiperazin-1-yl)quinazoline
• CAS NO: 316125-27-6
• Molecular Weight: 338.84
• Mol File: 316125-27-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-chlorophenyl)-4-(4-methylpiperazin-1-yl)quinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chlorophenyl)-4-(4-methylpiperazin-1-yl)quinazoline(316125-27-6)
• EPA Substance Registry System: 2-(4-chlorophenyl)-4-(4-methylpiperazin-1-yl)quinazoline(316125-27-6)

Safety Data

• Hazardous Substances Data: 316125-27-6(Hazardous Substances Data)

Upstream product

• 109-01-3 1-methyl-piperazine 
• 59490-94-7 4-chloro-2-(4-chlorophenyl)-quinazoline 

Relevant articles and documents

Synthesis, analgesic and anti-inflammatory evaluation of some novel quinazoline derivatives

Two series of some new 2,4,6-trisubstituted-quinazoline derivatives were prepared and screened for their analgesic, anti-inflammatory activity and acute toxicity. Four compounds were more potent analgesic agents than the reference drug Indomethacin and thirteen compounds showed significant anti-inflammatory activity. Seven compounds showed combined ability to inhibit both pain and inflammation. Compounds tested for acute toxicity showed no toxic symptoms or mortality rates 24 h post-administration implying their good safety margin.