316140-47-3

Upstream product

• 121449-70-5 3-bromo-3,5-dimethoxyphenol 
• 500-99-2 3,5-dimethoxyphenol 
• 23133-74-6 1-acetoxy-3,5-dimethoxy-benzene 

Downstream Products

• 121449-70-5 3-bromo-3,5-dimethoxyphenol 
• 3187-19-7 2,4-dimethoxysalicylic acid 
• 316140-42-8 (2'S)-(-)-1'-fluorooct-7'-en-2'-yl 2-hydroxy-4,6-dimethoxybenzoate 
• 316140-35-9 1'-fluorooct-7'-en-2'-yl 2-hydroxy-4,6-dimethoxybenzoate 
• 316140-44-0 (2'S)-(-)-1'-fluorooct-7'-en-2'-yl 2-allyl-4,6-dimethoxybenzoate 
• 316140-34-8 1'-fluorooct-7'-en-2'-yl 2-allyl-4,6-dimethoxybenzoate 
• 316140-41-7 1'-fluorooct-7'-en-2'-yl 2,4-dimethoxy-6-trifluoromethanesulfonatebenzoate 
• 316140-43-9 (2'S)-(-)-1'-fluorooct-7'-en-2'-yl 2,4-dimethoxy-6-trifluoromethanesulfonatebenzoate 

Relevant academic research and scientific papers

Enantioselective synthesis of a fluorinated analogue of the orsellinic acid-type twelve-membered lactone lasiodiplodin

The chemoenzymatic synthesis of the racemate and the one enantiomer of the fluorinated analogue 8 of the natural cyclooxygenase inhibitor lasiodiplodin is decribed. A lipase-mediated deracemization of the fluorohydrin 18 provided the chiral, nonracemic building block for the enantioselective synthesis of the title compound. The key step was the formation of the 12-membered lactene by a ring-closing metathesis.

An aryne route to cytosporone B and phomopsin C

The octaketide cytosporone B has been synthesized in six steps using 1,3,5-trihydroxybenzene as a starting material via aryne insertion reaction into a carbon-carbon σ-bond.