316181-13-2

Upstream product

• 4233-33-4 4-Phenyl-1,2,4-triazolidine-3,5-dione 
• 434-16-2 7-dehydrocholesterol 
• 316181-09-6 3-(methoxymethyloxy)-cholest-5,7-diene 
• 358681-28-4 (3S,10S,13R,14R,17R)-17-((R)-1,5-Dimethyl-hexyl)-3-methoxymethoxy-10,13-dimethyl-2,3,4,10,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene 
• 316181-11-0 C₃₇H₅₁N₃O₄ 

Relevant academic research and scientific papers

Synthesis and evaluation of 4-deacetoxyagosterol A as an MDR-modulator

4-Deacetoxyagosterol A was synthesized from ergosterol by utilizing reductive regioselective epoxy cleavage as a key reaction. This synthesized congener of agosterol A, a spongean MDR-modulator, showed similar MDR-modulating activity against KB CV-60 cell

Total synthesis of agosterol A: An MDR-modulator from a marine sponge

The first total synthesis of agosterol A, a modulator or multidrug resistance (MDR) mediated by P-gp and MRP1, and isolated from a marine sponge, was achieved from ergosterol by utilizing a regioselective epoxy-cleavage reaction and regioselective dehydro