316353-08-9Relevant academic research and scientific papers
Development of an efficient, regio- and stereoselective route to libraries based on the β-D-glucose scaffold
Hirschmann,Ducry,Smith III
, p. 8307 - 8316 (2000)
The design and execution of an efficient synthetic route for the sequential functionalization of the five hydroxyl substituents of β-D-glucose has been achieved. This strategy, based on the stereoselective glycosidation of thioglycosides, provides a new approach for the parallel construction of a wide variety β-D-glucose analogues and as such holds promise for solid-support library syntheses.
