3164-29-2

Basic information

• Product Name: Ammonium L-tartrate
• Synonyms: l-(+)-tartaric acid diammonium salt solution;AMMONIUMTARTRATE,CRYSTAL,REAGENT;L-Tartaric acid ammonium salt, Ammonium tartrate dibasic, Diammonium tartrate, L(+)-Tartaric acid diammonium salt;Ammonium tartrate solution dibasic;L-(+)-Tartaric acid solution diammonium salt, Diammonium tartrate solution;L-(+)-Tartaric acid diammonium salt, Diammonium tartrate;Azane (2R,3R)-2,3-dihydroxybutanedioic acid;(+)-L-Tartaric acid bisammonium salt
• CAS NO: 3164-29-2
• Molecular Formula: C₄H₆O₆*2H₃N
• Molecular Weight: 184.15
• EINECS: 221-618-9
• Product Categories: Industrial/Fine Chemicals
• Mol File: 3164-29-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: decomposes [CRC10]
• Boiling Point: 318.08°C (rough estimate)
• Flash Point: 209.4 °C
• Appearance: White semi-transparent/crystalline
• Density: 1.601 g/mL at 25 °C(lit.)
• Vapor Pressure: 1.26E-11mmHg at 25°C
• Refractive Index: 1.4800 (estimate)
• Storage Temp.: room temp
• Solubility: H2O: 1 M at 20 °C, clear, colorless
• Water Solubility: 63 g/L (15 ºC)
• Sensitive: Hygroscopic
• Stability: Stable. Incompatible with strong acids.
• BRN: 6120352
• CAS DataBase Reference: Ammonium L-tartrate(CAS DataBase Reference)
• NIST Chemistry Reference: Ammonium L-tartrate(3164-29-2)
• EPA Substance Registry System: Ammonium L-tartrate(3164-29-2)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 24/25-36-26
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 3
• RTECS: WW8050000
• TSCA: Yes
• Hazardous Substances Data: 3164-29-2(Hazardous Substances Data)

Usage

Chemical Properties

white crystalline powder

Uses

Different sources of media describe the Uses of 3164-29-2 differently. You can refer to the following data:
1. Textile industry, medicine.
2. Ammonium L-(+)-tartrate finds application in the textile and pharmaceutical industries. It is also used to study protein structural analysis, biochemicals and reagents, biological buffers, chelators and proteomics. It acts as a nitrogen source in biological applications and cell culture media. Further, it is used in the study of crystal optimization research and preliminary diffraction data analysis of the Smad1 MH1 domain bonded to a palindromic SBE DNA element.

Definition

ChEBI: An organic salt that is the diammonium salt of L-(+)-tartaric acid.

Flammability and Explosibility

Notclassified

Safety Profile

Poison by intravenous route. Moderately toxic by subcutaneous route. When heated to decomposition it emits very toxic fumes of NH3 and NOx.

Shipping

UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.

InChI:InChI=1/C4H6O6.2H3N/c5-1(3(7)8)2(6)4(9)10;;/h1-2,5-6H,(H,7,8)(H,9,10);2*1H3/t1-,2+;;

Synthetic route

(1S,4R)-4-aminocyclopent-2-ene-1-carboxylic acid methyl ester tartrate → (1S,4R)-(-)-methyl-4-aminocyclopent-2-en-1-carboxylate hydrochloride (138923-03-2) + diammonium tartate (3164-29-2)

Conditions	Yield
With ammonia In methanol; water at 20℃; for 1h; Product distribution / selectivity;

(1R,2R)-2-hydroxy-1-(methylamino)-1,2,3,4-tetrahydronaphthalene L-(+)-tartrate salt → (+)-(1R,2R)-trans-1,2,3,4-tetrahydro-1-(methylamino)2-naphthalenol (169106-10-9) + diammonium tartate (3164-29-2)

Conditions	Yield
With ammonium hydroxide; sodium chloride In tert-butyl methyl ether; water pH=> 8;

diammonium tartate (3164-29-2) + (2S,3S)-5-Methoxy-3-methyl-2-pentyl-3,4-dihydro-2H-pyrrole → (4R,5R)-4-Methyl-5-pentyl-pyrrolidin-2-ylideneamine; compound with 2,3-dihydroxy-succinic acid

Conditions	Yield
In methanol for 5h; Heating;

1-hexylamine hydrochloride (142-81-4) + diammonium tartate (3164-29-2) → (R,R)-(+)-di-N,N'-hexyltartramide (411235-31-9)

Conditions	Yield
at 20 - 180℃; for 0.416667h; microwave irradiation;

Upstream product

• 419563-22-7 (1S,4R)-4-aminocyclopent-2-ene-1-carboxylic acid methyl ester tartrate 

Relevant articles and documents

PRODUCTION METHOD FOR CIS-1-AMINO-4-HYDROXYMETHYL-2-CYCLOPENTENE OR ITS SALT

PROBLEM TO BE SOLVED: To provide a method capable of producing cis-1-amino-4-hydroxymethyl-2-cyclopentene or its salt with high selectivity and a high yield by using inexpensive reactants easily handleable. SOLUTION: Cis-1-amino-4-hydroxymethyl-2-cyclopentene represented by formula (II) or its salt is produced by mixing a cis-4-amino-2-cyclopentene-1-carboxylic ester salt represented by general formula (I) (wherein R1 is an optionally substituted alkyl, cycloalkyl, alkenyl, alkynyl, aryl, or aralkyl group; and A is an inorganic or organic acid residue) with a metal boron hydride complex compound under the condition that the stoichiometric ratio of the amount of the metal boron hydride complex compound to the amount of the cis-4-amino-2-cyclopentene-1-carboxylic ester salt is 1-10. COPYRIGHT: (C)2006,JPOandNCIPI