31652-77-4 Usage
Uses
Used in Pharmaceutical Industry:
2,3,5-tri-O-benzoyl-N-carbamoylpentofuranosylamine is used as an antiretroviral agent for its potential to inhibit the replication of retroviruses, such as HIV. Its unique structure allows it to interfere with the viral life cycle, providing a potential therapeutic option for the treatment of retroviral infections.
Used in Cancer Research:
2,3,5-tri-O-benzoyl-N-carbamoylpentofuranosylamine is used as a building block for the synthesis of nucleoside analogs with anti-cancer activities. Its unique structure can be modified to create novel nucleoside analogs that can target specific cancer cells, inhibiting their growth and proliferation.
Used in Antiviral Research:
2,3,5-tri-O-benzoyl-N-carbamoylpentofuranosylamine is used as a starting material for the development of new antiviral agents. Its unique structure can be modified to create nucleoside analogs with broad-spectrum antiviral activity, potentially providing new therapeutic options for the treatment of various viral infections.
Overall, 2,3,5-tri-O-benzoyl-N-carbamoylpentofuranosylamine shows promise as a versatile compound with potential therapeutic applications in the fields of antiretroviral, anti-cancer, and antiviral research. Its unique structure and properties make it an attractive candidate for further investigation and development.
Check Digit Verification of cas no
The CAS Registry Mumber 31652-77-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,6,5 and 2 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 31652-77:
(7*3)+(6*1)+(5*6)+(4*5)+(3*2)+(2*7)+(1*7)=104
104 % 10 = 4
So 31652-77-4 is a valid CAS Registry Number.
31652-77-4Relevant academic research and scientific papers
Okamura, Hidenori,Crisp, Antony,Hübner, Sarah,Becker, Sidney,Rovó, Petra,Carell, Thomas
, p. 18691 - 18696 (2019)
The RNA world hypothesis assumes that life on Earth began with nucleotides that formed information-carrying RNA oligomers able to self-replicate. Prebiotic reactions leading to the contemporary nucleosides are now known, but their execution often requires specific starting materials and lengthy reaction sequences. It was therefore proposed that the RNA world was likely proceeded by a proto-RNA world constructed from molecules that were likely present on the early Earth in greater abundance. Herein, we show that the prebiotic starting molecules bis-urea (biuret) and tris-urea (triuret) are able to directly react with ribose. The urea-ribosides are remarkably stable because they are held together by a network of intramolecular, bifurcated hydrogen bonds. This even allowed the synthesis of phosphoramidite building blocks and incorporation of the units into RNA. Investigations of the nucleotides’ base-pairing potential showed that triuret:G RNA base pairs closely resemble U:G wobble base pairs. Based on the probable abundance of urea on the early Earth, we postulate that urea-containing RNA bases are good candidates for a proto-RNA world.
