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Usage

Uses

Used in Scientific Research:
2-(2,4,5-trimethoxyphenyl)ethanamine is used as a research chemical for studying the effects of psychedelic compounds on the brain. Its potent agonist activity at serotonin receptors makes it a valuable tool in understanding the mechanisms of action and potential therapeutic applications of psychedelic substances.
Used in Psychopharmacology:
In the field of psychopharmacology, 2-(2,4,5-trimethoxyphenyl)ethanamine is used as a model compound to explore the interactions between psychedelic drugs and the serotoninergic system. This helps researchers to gain insights into the neurochemical basis of hallucinations, mood disorders, and other psychiatric conditions associated with altered serotonin signaling.
Used in Controlled Substances Regulation:
2-(2,4,5-trimethoxyphenyl)ethanamine is used as a reference substance in the regulation and control of Schedule I controlled substances in the United States. Its classification as a Schedule I substance highlights the importance of monitoring and controlling the distribution and use of potentially dangerous psychoactive compounds to prevent abuse and protect public health.

Upstream product

• 4460-86-0 asaraldehyde 
• 125438-24-6 2,4,5-trimethoxybenzaldehyde O-(trimethylsilyl)cyanohydrin 

Downstream Products

• 14430-23-0 5,6-dimethoxyindole 
• 106103-12-2 2,2,2-Trifluoro-N-[2-(2,4,5-trimethoxy-phenyl)-ethyl]-acetamide 
• 490-64-2 asaronic acid 

Relevant academic research and scientific papers

Preparation of Quinone Imine Ketals via Intramolecular Condensation of Amino-Substituted Quinone Monoketals. Anodic Oxidation Chemistry of Trifluoracetamide Derivatives of 1,4-Dimethoxybenzenes and 4-Methoxyphenols

Two routes have been developed to the previously unknown quinone imine ketal moiety.One involves a sequence of anodic oxidation of the N-trifluoroacetamide of a 2-(2,5-dimethoxyphenyl)ethylamine or 3-(2,5-dimethoxyphenyl)propylamine derivative to form the respective quinone bisketal followed by basic hydrolysis of the trifluoroacetamide linkage, acidic hydrolysis of the quinone bisketal to a quinone monoketal, and intramolecular condensation to form the quinone imine ketal.This method reuires an additional substituent at the 4-position (bromine or methoxy) to direct the regiochemistry of the quinone bisketal hydrolysis.The second method involves similar chemistry except that the anodic oxidation of a 4-methoxyphenol derivative directly affords the quinone monoketal.Hydrolysis of the trifluoroacetamide followed by an intramolecular condensation reaction affords the quinone imine ketal.Selected aspects of the chemistry of these compounds have been studied.Especially interesting is the reaction of a model quinone imine ketal with organolithium reagents.Either 1- or 2-substituted-5-methoxyindole is produced, depending upon the organolithium compound.