31665-45-9Relevant academic research and scientific papers
Design, synthesis and transformation of some heteroannulated 3-aminopyridines - Purine isosteres with exocyclic nitrogen atom
Iaroshenko, Viktor O.,Vilches-Herrera, Marcelo,Gevorgyan, Ashot,Mkrtchyan, Satenik,Arakelyan, Knar,Ostrovskyi, Dmytro,Abbasi, Muhammad S.A.,Supe, Linda,Hakobyan, Ani,Villinger, Alexander,Volochnyuk, Dmitriy M.,Tolmachev, Andrei
supporting information, p. 1217 - 1228 (2013/02/23)
The synthesis of 1-deazapurines and isosteres bearing the exocyclic nitrogen atom at position-1 was developed basing on the formal [3+3]-cyclization reaction of nitro-malonaldehyde with the set of electron-excessive aminoheterocycles. Through the function
Transition-metal-catalyzed arylation of 1-deazapurines via C-H bond activation
Iaroshenko, Viktor O.,Ali, Iftikhar,Mkrtchyan, Satenik,Semeniuchenko, Volodymyr,Ostrovskyi, Dmytro,Langer, Peter
supporting information, p. 2603 - 2608 (2013/01/15)
Transition-metal-catalyzed arylation of imidazo[4,5-b]pyridines (known as 1-deazapurines) is reported. 1-Deazapurines were synthesized from 5-aminoimidazoles, generated in situ by the reaction of methyl N-(cyanomethyl)formimidate with primary amines. Geor
3-methoxalylchromone - A versatile reagent for the regioselective synthesis of 1-desazapurine
Ostrovskyi, Dmytro,Iaroshenko, Viktor O.,Ali, Iftikhar,Mkrtchyan, Satenik,Villinger, Alexander,Tolmachev, Andrei,Langer, Peter
experimental part, p. 133 - 141 (2011/03/19)
The reaction of 5-amino-1H-imidazoles with 3-methoxalylchromone provided a set of imidazo[4,5-b]pyridines (1-des-azapurines) bearing the CO2Me substituent at the -position of the pyridine core. The corresponding acids were synthesized by subseq
An efficient synthesis of 6-nitro-and 6-amino-3H-imidazo[4,5-b ]pyridines by cyclocondensation of 1-substituted 1H-imidazol-5-amines with 3-nitro-4H-chromen-4-one
Ostrovskyi, Dmytro,Iaroshenko, Viktor O.,Petrosyan, Andranik,Dudkin, Sergii,Ali, Iftikhar,Villinger, Alexander,Tolmachev, Andrei,Langer, Peter
experimental part, p. 2299 - 2303 (2010/11/03)
The reaction of 3-nitro-4H-chromen-4-one with in situ generated 1-substituted 5-amino-1H-imidazoles affords a set of 1-substituted 6-nitro-3H-imidazo[4,5-b]pyridines which represent potential adenosine deaminase (ADA) inhibitors. Reduction of the nitro group results in the formation of the corresponding 6-amino-3H-imidazo[4,5-b]pyridines. Georg Thieme Verlag Stuttgart - New York.
